Results 21 to 30 of about 65,696 (224)

Azides in the Synthesis of Various Heterocycles

Molecules, 2022
In this review, we focus on some interesting and recent examples of various applications of organic azides such as their intermolecular or intramolecular, under thermal, catalyzed, or noncatalyzed reaction conditions.
AbdElAziz A. Nayl, Ashraf A. Aly, Wael A. A. Arafa, Ismail M. Ahmed, Ahmed I. Abd-Elhamid, Esmail M. El-Fakharany, Mohamed A. Abdelgawad, Hendawy N. Tawfeek, Stefan Bräse   +8 more
doaj   +1 more source

Iron(II)-Catalyzed Aerobic Biomimetic Oxidation of N-Heterocycles. [PDF]

, 2023
Herein, an iron(II)-catalyzed biomimetic oxidation of N-heterocycles under aerobic conditions is described. The dehydrogenation process, involving several electron-transfer steps, is inspired by oxidations occurring in the respiratory chain.

core   +2 more sources

An electrochemical gram-scale protocol for pyridylation of inert N-heterocycles with cyanopyridines

STAR Protocols, 2022
Summary: Here, we present a protocol to decyanopyridate inert N-heterocycles access to N-fused heterocycles via the mechanism of dual proton-coupled electron transfer (PCET).
Cong Niu, Jianjing Yang, Kelu Yan, Jiafang Xie, Wei Jiang, Bingwen Li, Jiangwei Wen   +6 more
doaj   +1 more source

Umpolung Of Electron-Rich Heteroarenes With Hypervalent Iodine Reagents

, 2021
Five-membered heterocycles are well known for their innate nucleophilicity. In contrast, reaction of these heterocycles as electrophiles is less established and has become only recently an intensively investigated research area in synthetic chemistry ...
Nandi, Raj Kumar, Waser, Jerome, Pal, Pamela, Pamela Pal, Raj Kumar Nandi, Jerome Waser   +5 more
core   +1 more source

Phosphorus-Sulfur Heterocycles Incorporating an O-P(S)-O or O-P(S)-S-S-P(S)-O Scaffold: One-Pot Synthesis and Crystal Structure Study

Molecules, 2017
A new one-pot preparative route was developed to synthesize novel organophosphorus-sulfur heterocycles via the reaction of the four-membered ring thionation reagent [2,4-diferrocenyl-1,3,2,4-diathiadiphosphetane 2,4-disulfide (FcLR, a ferrocene analogue ...
Guoxiong Hua, Kate Davidson, David B. Cordes, Junyi Du, Alexandra M. Z. Slawin, J. Derek Woollins   +5 more
doaj   +1 more source

Enantioselective construction of six- and seven-membered triorgano-substituted silicon-stereogenic heterocycles

Nature Communications, 2021
Enantioenriched medium-sized silicon-stereogenic heterocycles are in high demand due to the potential use in functional materials. Here, the authors show a rhodium-catalyzed enantioselective synthesis of six- and seven-membered tri-organosubstituted ...
Shuyou Chen, Delong Mu, Pei-Lin Mai, Jie Ke, Yingzi Li, Chuan He   +5 more
doaj   +1 more source

A Brief Review on the Synthesis of the N-CF₃ Motif in Heterocycles

Molecules, 2023
The trifluoromethyl group is widely recognized for its significant role in the fields of medicinal chemistry and material science due to its unique electronic and steric properties that can alter various physiochemical properties of the parent molecule ...
Zizhen Lei, Wenxu Chang, Hong Guo, Jiyao Feng, Zhenhua Zhang   +4 more
doaj   +1 more source

The oxime portmanteau motif : released heteroradicals undergo incisive EPR interrogation and deliver diverse heterocycles [PDF]

, 2014
OA funded through the RCUK OA block grant.Selective syntheses are now available for compounds of many classes, based on C-centered radicals, exploiting a diverse range of mechanisms.
John C. Walton, Walton, John Christopher, Walton, John Christopher; id_orcid   +2 more
core   +1 more source

C-H Functionalization Reactions of Unprotected N-Heterocycles by Gold Catalyzed Carbene Transfer [PDF]

, 2020
The C-H functionalization reaction of N-heterocycles with unprotected N-H group is one of the most step-economic strategies to introduce functional groups without the need of installation and removal of protecting groups.
Polina, Aseeva, Thanh Vinh, Nguyen, Claire, Empel, Chao, Pei, Sripati, Jana, Rene, Koenigs   +5 more
core   +2 more sources

In silico screening of drug-like molecules for the treatment of cardiovascular diseases on the basis of five-membered privileged heterocycles

Фармацевтичний журнал, 2019
Among various heterocyclic systems, the derivatives of five-membered heterocycles are of special interest. Most of the above mentioned heterocycles are treatred as so-called privileged structures in modern medicinal chemistry.
І. V. Drapak
doaj   +1 more source