Results 31 to 40 of about 18,930 (288)
Infrared spectra of acid azides, carbamyl azides and other azido derivatives
, 1963 The infrared spectra of organic acid azides, carbamyl azides, vinyl azides and alphaazido ethers, thioethers and amines have been investigated in detail. The acid azides and the carbamyl azides show the characteristic N3 and carbonyl absorptions and have
C.N.R. Rao +11 more
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Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Solid-phase enrichment and analysis of electrophilic natural products
Beilstein Journal of Organic Chemistry, 2017 In search for new natural products, which may lead to the development of new drugs for all kind of applications, novel methods are needed. Here we describe the identification of electrophilic natural products in crude extracts via their reactivity ...
Frank Wesche, Yue He, Helge B. Bode
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Access to Unsupported Iminobismuthane and Tetraazabismole Species Enabled by a Rigid and Bulky Organobismuthinidene. [PDF]
Angew Chem Int Ed EnglBy employing a sterically bulky monocoordinate bismuthinidene, the synthesis and characterization of the first examples of an unsupported iminobismuthane and tetraazabismole was achieved via reactions with organic azides. The corresponding amines could be accessed by reduction, leading to the regeneration of the Bi(I) compound. Hence, we also highlight
Potocnik M +9 more
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Linking of Alcohols with Vinyl Azides
, 2016 A protocol to link alcohols with vinyl azides has been established through fluoro- or bromo-alkoxylation of vinyl azides to provide α-alkoxy-β-haloalkyl azides.
Bengang Xing (1597777) +9 more
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Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Acta Crystallographica Section E: Crystallographic Communications, 2021 The title compound (E)-1,3-dimethyl-2-[3-(4-nitrophenyl)triaz-2-enylidene]-2,3-dihydro-1H-imidazole, C11H12N6O2, has monoclinic (C2/c) symmetry at 100 K.
Hector Mario Heras Martinez +4 more
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Molecular Oncology, EarlyView.Loss of eIF5A rewires thapsigargin‐mediated endoplasmic reticulum stress responses in multiple myeloma cells by selective translation of mRNA transcripts, consequently dampening thapsigargin‐induced unfolded protein response (UPR) activation and shifting the balance from induction of apoptosis toward cell survival and proliferation.
Demi Both +7 more
wiley +1 more source
, 1973 A review of the decomposition of alkyl and aryl azides by thermolysis and photolysis has been accomplished. Organic azides are a very distinct species that undergo its own unique reactions. Azides decompose to form an electron deficient nitrogen having a
Nelson, Edward D.
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Alkynes and Azides: Not Just for Click Reactions. [PDF]
, 2012 We recently reported two unexplored reactivities of alkynes and azides. The first method reacts nucleophilic alkynes and electrophilic azides to synthesize sulfonyl-substituted 1,5-disubstituted-1,2,3-triazoles.
Croatt, Mitchell +2 more
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