Results 41 to 50 of about 36,523 (324)

ACC Synthase Genes Related to Cold-dependent Ripening in Pear Fruit [PDF]

open access: yes, 2004
The differential regulation of ACC synthase genes has been studied in pear cultivars that either require a long chilling treatment before they are capable of ripening (‘Passe-Crassane’, PC) or not (‘Old-Home’, OH) and in OH x PC hybrids having no (A16)
El-Sharkawy, Islam   +3 more
core   +1 more source

Integrative miRNOMe profiling reveals the miR‐195‐5p–CHEK1 axis and its impact on luminal breast cancer outcomes

open access: yesMolecular Oncology, EarlyView.
In luminal (ER+) breast carcinoma (BC), miRNA profiling identified miR‐195‐5p as a key regulator of proliferation that targets CHEK1, CDC25A, and CCNE1. High CHEK1 expression correlates with worse relapse‐free survival after chemotherapy, especially in patients with luminal A subtype.
Veronika Boušková   +14 more
wiley   +1 more source

Changes of bone turnover markers and bone mineral density among postmenopausal Thai women with osteoporosis receiving generic risedronate

open access: yesBMC Women's Health
Background Osteoporosis has been recognized as a significant health issue in Thailand. Pharmacological interventions are important way to prevent fracture. However, one of the main challenges in selecting a medication is high cost, particularly for brand-
Ammarin Suwan   +7 more
doaj   +1 more source

Severity of climacteric symptoms among Peruvian women from an urban coastal community and a rural Andean community

open access: yesRural and Remote Health, 2021
Introduction: The aim of this study was to evaluate the severity of climacteric symptoms among two Peruvian communities, adjusted for sociodemographic and clinical variables in climacteric women.
Renato Beas   +5 more
doaj   +1 more source

Cognitive Resilience in Apolipoprotein ε4 Carrier Women Predicted by Neuron‐Derived Extracellular Vesicles

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The Apolipoprotein (APOE) ε4 allele is the strongest genetic risk factor for late‐onset Alzheimer's disease (AD); however, many ε4 carriers remain cognitively intact into old age. Leveraging plasma neuron‐derived extracellular vesicles (NDEVs), we sought to identify biomarkers of cognitive resilience and their interplay with APOE ...
Apostolos Manolopoulos   +17 more
wiley   +1 more source

Metabolic profiling reveals coordinated switches in primary carbohydrate metabolism in grape berry (Vitis vinifera L.), a non-climacteric fleshy fruit [PDF]

open access: yes, 2013
Changes in carbohydrate metabolism during grape berry development play a central role in shaping the final composition of the fruit. The present work aimed to identify metabolic switches during grape development and to provide insights into the timing of
Dai, Z.   +5 more
core   +2 more sources

Matrix Tropism Influences Endometriotic Cell Attachment Patterns

open access: yesAdvanced Functional Materials, EarlyView.
The influence of substrate stiffness and multicellular coculture on endometriotic cell attachment to extracellular matrix‐laden microarrayed islands is reported. This model investigates early endometriotic cell attachment, aiming to capture “lesion initiation events”.
Hannah S. Theriault   +7 more
wiley   +1 more source

Recent Developments on the Role of Ethylene in the Ripening of Climacteric Fruit [PDF]

open access: yes, 2001
It has long been recognised that ethylene plays a major role in the ripening process of climacteric fruit. A more thorough analysis, however, has revealed that a number of biochemical and molecular processes associated with climacteric fruit ripening ...
Bouzayen, Mondher   +8 more
core  

Methods used in cross-culturalcomparisons of vasomotor symptoms and their determinants [PDF]

open access: yes, 2011
Methodological differences among studies of vasomotor symptoms limit rigorous comparison or systematic review. Vasomotor symptoms generally include hot flushes and night sweats although other associated symptoms exist.
Anderson, Debra   +3 more
core   +2 more sources

Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes

open access: yesAdvanced Functional Materials, EarlyView.
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth   +2 more
wiley   +1 more source

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