Results 31 to 40 of about 4,576,993 (310)

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

open access: yesFEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani   +6 more
wiley   +1 more source

Strengthening Climate-Resilient Agricultural Systems in South Asia: CCAFS South Asia Regional Meeting Report [PDF]

open access: yes, 2020
State of the art discourse on agriculture and climate change, lays emphasis on the dual role of agriculture in adapting to and mitigating climate change.
CGIAR Research Program on Climate Change, Agriculture and Food Security
core  

Perceptions of time in relation to climate change [PDF]

open access: yes, 2014
Time is at the heart of understanding climate change, from the perspective of both natural and social scientists. This article selectively reviews research on time perception and temporal aspects of decision making in sociology and psychology.
Boomsma, C   +3 more
core   +2 more sources

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

open access: yesFEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao   +3 more
wiley   +1 more source

Why human connection is the true metric of research success

open access: yesFEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan   +3 more
wiley   +1 more source

Declaração de Fortaleza Declaration of Fortaleza

open access: yesSustentabilidade em Debate, 2010
Declaração de FortalezaDeclaration of ...
2010 International Conference on Climate, Sustainability and Development in Semi-arid Regions
doaj  

Hysteresis of the Antarctic Ice Sheet With a Coupled Climate‐Ice‐Sheet Model

open access: yesGeophysical Research Letters
The stability of the Antarctic ice sheet under different fixed CO2 levels and orbital configurations is explored using a coupled climate‐ice sheet model, starting from either a pre‐industrial ice sheet or an ice‐free, isostatically rebounded geometry ...
G. Leloup   +4 more
doaj   +1 more source

Pace Energy & Climate Center 2016 Annual Report [PDF]

open access: yes, 2017
The Center staff and many allies are deeply involved in the business of electric utility transformation. We live and work in a remarkable time. Decades of steady, thoughtful leadership on clean energy issues is now bearing fruit. Clean energy is not just
Pace Energy & Climate Center
core   +1 more source

Governing carbon mitigation and climate change within local councils: a case study of Adelaide, South Australia [PDF]

open access: yes, 2012
There is growing concern about climate change impacts on local government areas. In Australia, the federal carbon tax (from 1 July 2012) will also increase costs for local councils. This paper evaluates what carbon mitigation (i.e.
Zeppel, Heather
core   +3 more sources

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

open access: yesFEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho   +4 more
wiley   +1 more source

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