Results 61 to 70 of about 1,390,750 (253)

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling, Mark D. Parker, Sven Kerst, Richard A. Pasternack, Jacob Tondreau, Marjolein Breur, Gemma M. van Rooijen‐van Leeuwen, Davide Tonduti, Ettore Salsano, Alejandra Darling, Joanna A. E. van Wijk, Susanna Törnroth‐Horsefield, Marianna Bugiani, Petra J. W. Pouwels, Quinten Waisfisz, Marjo S. van der Knaap, Rogier Min   +16 more
wiley   +1 more source

Are point measurements in a bog representative of their surrounding area? [PDF]

Mires and Peat, 2019
Descriptions of abiotic properties in bogs are often based on point measurements. To assess whether these point measurements are representative of their surrounding area, depth to water table (DTW), soil moisture, pH, electrical conductivity (EC), the ...
S.A. Howie, H.J. van Meerveld
doaj   +1 more source

From time uncertainties to climate-smart agriculture in the Sudano-Sahelian zone of Cameroon. [P2] [PDF]

, 2015
In the Sudano-Sahelian zone of Cameroon, the acceleration of drying of landscape has created uncertainty of agricultural practices too related to natural data.
Bring,, Fofiri Nzossié, Eric Joël, Temple, Ludovic, wakponou, anselme   +3 more
core  

The Role of Calcitonin Gene‐Related Peptide in High‐Altitude Headache: A Prospective Field Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective High‐altitude headache (HAH) is a common neurological condition associated with rapid ascent to high altitude. The pathophysiological mechanisms underlying HAH remain incompletely understood. Calcitonin gene‐related peptide (CGRP), a neuropeptide implicated in migraine pathophysiology, may play a key role in the pathophysiology of ...
Roman Schniepp, Ludwig Karrasch, Helena Breitenstein, Andreas Straube, Katharina Kamm   +4 more
wiley   +1 more source

Roof renewal disparities widen the equity gap in residential wildfire protection

Nature Communications
Wildfires are having disproportionate impacts on U.S. households. Notably, in California, over half of wildfire-destroyed homes (54%) are in low-income areas.
Sebastian Reining, Moritz Wussow, Chad Zanocco, Dirk Neumann   +3 more
doaj   +1 more source

Relationship Between Neurologic Symptoms and Signs and FMR1 Genotype in Premutation Carriers

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Fragile X‐associated Tremor/Ataxia Syndrome (FXTAS) is the most severe late‐onset condition caused by a premutation in the FMR1 gene, characterized by expanded CGG triplet repeats of 55–200. Clinical presentations of FXTAS, including gait ataxia, kinetic tremor, cognitive decline, and rare Parkinsonism, are linked to ...
Flora Tassone, Freddy Chafota, Miguel E. Rentería, Randi J. Hagerman, Ellery Santos, Anna Atkinson, Nicholas G. Martin, Elsdon Storey, Danuta Z. Loesch   +8 more
wiley   +1 more source

Rheology, strength and durability performance of bentonite-enhanced high-performance concrete

Scientific Reports
Bentonite has been widely studied as a cementitious additive in conventional concrete, but its integration into high-performance concrete has not been extensively explored.
M. Achyutha Kumar Reddy, Veerendrakumar C. Khed, Naga Chaitanya Kavuri   +2 more
doaj   +1 more source

MCA4climate: A Practical Framework for Planning Pro-Development Climate Policy [PDF]

, 2011
MCA4climate is a major new UNEP initiative providing 1 Introduction practical assistance to governments in preparing their climate change mitigation and adaptation plans and strategies.
Bristow, Sophy, Puig, Daniel, Scrieciu, Şerban   +2 more
core  

Has climate change taken prominence over biodiversity conservation? [PDF]

, 2014
The growing prominence of climate change has led to concerns that other important environmental issues, such as biodiversity loss, are being overshadowed.
Crees, Jennifer, Davies, Zoe G., MacMillan, Douglas C., Smith, Robert J., Veríssimo, Diogo   +4 more
core   +1 more source

Advancing Age Modulates Associations Between Cognitive Impairment and Brain Volumes in Early MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Cognitive impairment is common in multiple sclerosis (MS), but manifestations following the first demyelinating event are relatively unexplored. We investigated cross‐sectional associations between magnetic resonance imaging (MRI)–derived brain volumes and the presence of cognitive impairment outcomes five years after the first ...
Piriyankan Ananthavarathan, Marco Pitteri, Michael Foster, Sara Collorone, Sara Salama, Elisa Colato, Ferran Prados, Baris Kanber, Marios Yiannakas, Claudia A. M. Gandini Wheeler‐Kingshott, Indran Davagnanam, Frederik Barkhof, Declan Chard, Olga Ciccarelli, Ahmed Toosy   +14 more
wiley   +1 more source