Results 131 to 140 of about 897,845 (317)

Climate change adaptation through coastal and use management: The context of environmental justice [PDF]

, 2010
Despite an increasing literary focus on climate change adaptation, the facilitation of this adaptation is occurring on a limited basis (Adger et al.
Allen Owens, Marcia, Hall, Reginald, Marshall, Ariana, Stokes, IV, Shereitte   +3 more
core  

Targeting the PDK1/c‐Myc/SOX10 Signaling in Oligodendrocytes Alleviates Neuropathic Pain

Advanced Science, EarlyView.
This work reveals that oligodendrocyte homeostasis, mediated by PDK1, is a critical determinant of neuropathic pain (NPP) pathogenesis. Disruption of PDK1 in oligodendrocytes impairs SOX10‐dependent myelination programs through c‐Myc accumulation, leading to disrupted myelination and the pathophysiology of NPP.
Pingping Qiao, Lifang Guo, Guochao Yang, Chaoli Huang, He Wang, Jian‐Jun Yang, Guiquan Chen, Yimin Hu   +7 more
wiley   +1 more source

Alternating High‐Fat and Polysaccharide Diets Modulates Gut Phage‐Bacterial Interplay

Advanced Science, EarlyView.
This study reveals how alternating high‐fat and polysaccharide diets reshape the human gut virome and enhance phage‐bacteria interactions. Using large‐scale metagenomic meta‐analysis and a time‐resolved mouse model, the authors show that diets strongly modulate phage abundance, lifestyle, and gene exchange, offering new insights into nutrition‐guided ...
Fengxiang Zhao, Ruiqi Zhang, Rujun Wei, Huimin Fan, Yongfei Hu, Wenyu Shi, Jinfeng Wang   +6 more
wiley   +1 more source

County‐Scale Climate Projections Over Minnesota and the Effects of Lakes

Water Resources Research
Climate projections for three future shared socioeconomic pathway scenarios from six CMIP6 global climate models (GCMs) were dynamically downscaled over Minnesota with the regional Weather Research and Forecasting model coupled to a lake model at 4‐km ...
Stefan Liess, Heidi A. Roop, Tracy E. Twine, Suzanna Clark, Dena Coffman, Dhondup Dolma, Amanda Farris, Alejandro Fernandez, Jack Gorman, Nathan Meyer   +9 more
doaj   +1 more source

Maternal Preconception Antibiotic Exposure Disrupts Microbial Succession: A Transgenerational Risk for Offspring Gut Mucosal Immaturity and Colitis Susceptibility

Advanced Science, EarlyView.
This study reveals that maternal antibiotic exposure prior to conception disrupts intergenerational gut microbial succession. By enhancing maternal‐offspring microbial transmission, altering microbial developmental trajectories and increasing selective pressures during community assembly, these disturbances lead to persistent gut mucosal immaturity and
Yuzhu Chen, Ruqiao Duan, Cunzheng Zhang, Gaonan Li, XiaoLin Ji, Qi Zhang, Fei Pei, Kun Wang, Liping Duan   +8 more
wiley   +1 more source

Genome‐Wide Association Study Reveals Insect Genetics and Microbial Symbiont Effects on Susceptibility of Diaphorina citri to the Citrus Greening Pathogen, Candidatus Liberibacter Asiaticus

Advanced Science, EarlyView.
This study investigates the genetic and microbial factors influencing the susceptibility of Diaphorina citri to the citrus greening pathogen Candidatus Liberibacter asiaticus (CLas), employing a microbiome Genome Wide Association Study. The research identifies a key gene encoding an MFS‐type transporter contributing to CLas infectivity and abundance in
Kai Liu, Qingcui He, Zeyue Lin, Shixuan Huang, Zichun Zhong, Pingyang Zhu, Mengge Gao, Luyao Zhao, Han Jin, Guiting Wu, Gurr M. Geoff, Qunxin Han, Rui Pang   +12 more
wiley   +1 more source

Climate change impacts and adaptation in U.S. Rocky Mountain high-elevation ecosystems

Arctic, Antarctic, and Alpine Research
From a resource management perspective, climate change is considered to be one of the main threats to high-elevation ecosystems. However, these valuable ecosystems present unique challenges to climate change adaptation (actions in response to ...
Meagan F. Oldfather, Alyson Ennis, Brian W. Miller, Kyra Clark-Wolf, Imtiaz Rangwala, Hailey Robe, Caitlin Littlefield   +6 more
doaj   +1 more source

Assessment of governance strategies for climate adaptation in Flanders / Belgium [PDF]

, 2010
Climate discourse in recent decades has mainly focused on the issue of mitigation. Through a better understanding and assessment of climate challenges, adaptation arises as a complementary strategy to mitigation.
Allaert, Georges, Leinfelder, Hans, Verhofstede, Björn   +2 more
core   +1 more source

Evolutionary adaptation to climate change

Evolution Letters
AbstractWhen the notion of climate change emerged over 200 years ago, few speculated as to the impact of rising atmospheric temperatures on biological life. Tens of decades later, research clearly demonstrates that the impact of climate change on life on Earth is enormous, ongoing, and with foreseen effects lasting well into the next century. Responses
Edelsparre, Allan, Fitzpatrick, Mark, Saastamoinen, Marjo, Teplitsky, Céline   +3 more
openaire   +5 more sources

Gemella morbillorum Promotes Colorectal Carcinogenesis: LPBDCP‐Mediated Invasion Activates Ras Signaling and Destabilizes p53

Advanced Science, EarlyView.
ABSTRACT Gut microbiota dysbiosis promotes colorectal cancer (CRC) tumorigenesis. A global fecal metagenomic analysis identified Gemella morbillorum as a key contributor to the CRC‐associated microbiota. Fluorescence in situ hybridization revealed that Gemella morbillorum is enriched in CRC tumor tissues compared to adjacent normal tissues.
Zhen Wang, Jia Zhang, Haojie Lu, Jingjing Ni, Shuaishuai Yang, Yuting Shi, Shuo Zhang, Pei Zhang, Li Liu   +8 more
wiley   +1 more source