Results 161 to 170 of about 879,580 (295)

Vitamin D Regulates Olfactory Function via Dual Transcriptional and mTOR‐Dependent Translational Control of Synaptic Proteins

Advanced Science, EarlyView.
Vitamin D (VitD) modulates olfactory function by remodeling dendrodendritic synapses in tufted cells through vitamin D receptor‐dependent transcriptional and translational mechanisms. VitD regulates synaptic protein translation partially via mTOR signaling.
Pengcheng Ren, Renhe Cao, Xiaoshan Ye, Wenbin Pang, Qingshang Bi, Meihui Huang, Qionglin Zhou, Dan Ye, Wei Xiang, Le Xiao   +9 more
wiley   +1 more source

Climate change adaptation

Oñati Socio-Legal Series, 2018
This paper contrasts knowledge frames for climate change and displacement. First the paper explains the abstract human rights arguments about displacement in climate change and disaster. In contrast, management and claims under lawsuits about climate change and displacement are place-based.
openaire   +1 more source

USP9X as a Candidate Mediator of Prenatal Aspirin‐Induced Ovarian Reserve Reduction in Offspring Mice

Advanced Science, EarlyView.
This study suggests that prenatal aspirin exposure is associated with reduced ovarian reserve in offspring, associated with HDAC1‐linked epigenetic downregulation of Usp9x as a candidate mechanism. These preclinical findings provide new insights into fetal‐origin ovarian disorders and contribute to the evidence base concerning aspirin's gestational ...
Yating Li, Caiyun Ge, Wai Yen Yim, Hui Feng, Tiancheng Wu, Lu Chen, Qiaohua Xiong, Shumin Pan, Mei Wang, Huijun Chen, Yuanzhen Zhang, Hui Wang   +11 more
wiley   +1 more source

Climate adaptation and functional constraints drive pollen evolution in Apiales. [PDF]

New Phytol
Baczyński J, Spalik K, Burke JM, Banasiak Ł.   +3 more
europepmc   +1 more source

Climate change and adaptation of small-scale cattle and sheep farmers [PDF]

The main objective of this study was to investigate the factors that affected the decision of small-scale farmers who kept cattle and sheep on whether to adapt or not to climate changes.
Anim, F.D.K., Mandleni, B.
core   +1 more source

Chromatin Topology Reconfiguration Orchestrates Thermotolerant Male Fertility via GhAL5 in Cotton

Advanced Science, EarlyView.
This study investigates cotton’s high‐temperature (HT) response using multi‑omics. Dynamic 3D genome changes drive expression bias affecting male fertility. The tolerant line shows controlled chromatin dynamics, while the sensitive line exhibits overactivation.
Yanlong Li, Jing Yang, Weiran Wang, Chunyang Zuo, Liuling Pei, Yizan Ma, Rui Zhang, Yaru Fan, Huanhuan Ma, Yawei Li, Ruizhen Liu, Shuangxia Jin, Longfu Zhu, Jie Kong, Xianlong Zhang, Ling Min   +15 more
wiley   +1 more source

Business-as-usual and fantasy planning - an analysis of equity within climate adaptation planning for sanitation in Nairobi. [PDF]

PLoS One
Hyde-Smith LK, Ddiba D, Dickin S, Kiogora D, Mdee AL, Reinfelder V, Roelich KE, Evans B.   +7 more
europepmc   +1 more source

Barriers to build asset adaptation in private service sector [PDF]

It is becoming increasingly acknowledged that adaptation and mitigation are equally important and often interrelated approaches to climate change. Recent adaptation initiatives in the UK include the promotion of many policies, reporting and economic ...
Ali, Fuad, Desai, Apeksha, Jones, Keith
core  

Gut Microbiota‐Derived Anandamide Mediates the Therapeutic Effects of Urolithin A on Alcohol‐Induced Cognitive and Social Dysfunction via CB1R‐DRD2‐RAP1 Signaling Axis

Advanced Science, EarlyView.
This study reveals that Urolithin A (UA) counteracts alcohol‐induced cognitive and social dysfunction (AICSD) via a gut microbiome‐dependent mechanism. UA‐enriched Bacteroids sartorii and Parabacteroids distasonis elevate anandamide (AEA), which activates the CB1R‐DRD2‐Rap1 signaling cascade to drive synaptic repair and reduce neuroinflammation ...
Hongbo Zhang, Zibin Li, Yao Xiao, Ji Bian, Caian He, Chao Liu, Lan Gong, Lin Han, Zhigang Liu, Min Wang   +9 more
wiley   +1 more source

Local Climate Adaptation in Chinese Indigenous Pig Genomes. [PDF]

Animals (Basel)
Liu Y, Xu Y, Li G, Ayalew W, Zhong Z, Zhang Z.   +5 more
europepmc   +1 more source