Results 181 to 190 of about 897,845 (317)

Conventional approaches to indicators and metrics undermine urban climate adaptation. [PDF]

NPJ Urban Sustain
Olazabal M, Mansur AV, Sahay S, Helmke-Long L, Granceri Bradaschia M, Villaverde A, Garmendia L, Dacosta Aboagye P, Sharifi A, Asamoah O, Mwangi P, Lewis W, Izaola B, Murtagh E, Feldman I.   +14 more
europepmc   +1 more source

Potential climate effects on Japanese rice productivity [PDF]

Adaptation to climate change has become an important policy question in recent years. Agriculture is the economic activity most sensitive to climate change. We evaluate the dynamic effects of productivity change and individual efforts to adapt to climate
Kondo, Katsunobu, Managi, Shunsuke, Masuda, Kiyotaka, Tanaka, Kenta, Yamamoto, Yasutaka   +4 more
core   +1 more source

mGluR5 in ECCCK to BLA Circuit Modulates Depressive‐Like Phenotypes through CCK Signaling

Advanced Science, EarlyView.
Dysregulation of mGluR5 and CCK signaling contributes to major depressive disorder, yet circuit‐level mechanisms remain unclear. Here, the ECCCK→BLA pathway is identified as a critical regulator of affective behavior. mGluR5 modulates synaptic function and CCK signaling within this circuit, controlling stress susceptibility and depressive‐like states ...
Muhammad Asim, Huajie Wang, Gao Qianqian, Abdul Waris, Jufang He   +4 more
wiley   +1 more source

Total Costs and Budgetary Effects of Adaptation to Climate Change: An Assessment for the European Union [PDF]

Adaptation to climate change is gaining increasing relevance in the public debate of climate policy. However, detailed and regionalised cost estimates as a basis for cost-benefit-analyses are rare.
Christiane Reif, Daniel Osberghaus
core  

The Trichinella Super‐Pangenome Reveals the Evolution of Encapsulation and Predicted Host–Parasite Protein Interactions

Advanced Science, EarlyView.
ABSTRACT The muscle capsule of Trichinella is a critical structure that impedes immune attacks and drug penetration, yet the molecular mechanisms underlying its formation remain poorly understood. Using a high‐quality super‐pangenome comprising 12 Trichinella species, we compared extensive genomic variations between encapsulating and non‐encapsulating ...
Qingbo Lv, Yi Liu, Ning Xu, Xiao Zhang, Yaming Yang, Chengyao Li, Hanhai Mao, Mingyuan Liu, Xiaolei Liu   +8 more
wiley   +1 more source

Spatiotemporal modeling of urban green space connectivity and landscape structure for climate adaptation in Tehran, Iran. [PDF]

PLoS One
Omidighalehmohammadi Z, Morovati M, Karami P, Parvar Z.   +3 more
europepmc   +1 more source

MEOX1 Coordinates Autocrine‐Paracrine Programs via SPHK1/S1P to Promote Lymph Node Metastasis in Ovarian Cancer

Advanced Science, EarlyView.
In ovarian cancer, MEOX1 activates the SPHK1/S1P pathway to promote both tumor progression and tumor–stroma crosstalk. MEOX1‐dependent signaling drives CAF activation, enhances VEGF‐C expression, and stimulates lymphangiogenesis, ultimately facilitating lymph node metastasis.
Jiajia Li, Xiuling Zhi, Qianhan Lin, Yating Sun, Yihua Sun, Zulimire Abudousalamu, Mengyang Xue, Chang Zheng, Xiaotian Li, Liangqing Yao, Mo Chen   +10 more
wiley   +1 more source

Climate adaptation and functional constraints drive pollen evolution in Apiales. [PDF]

New Phytol
Baczyński J, Spalik K, Burke JM, Banasiak Ł.   +3 more
europepmc   +1 more source

Glomage: A Multimodal Platform for High‐Content Morphological and RNA Profiling of Glomeruli in Zebrafish and Mouse Models

Advanced Science, EarlyView.
Understanding how glomeruli, the kidney's filtration units, function in intact tissue remains challenging. Glomage enables rapid 3D imaging and quantitative analysis of entire glomeruli from zebrafish larvae and mice. This approach allows scalable cell quantification and detection of structural changes, advancing kidney disease research and ...
Maximilian Schindler, Tim Lange, Sophia‐Marie Bach, Soeren S. Lienkamp, Nicole Endlich   +4 more
wiley   +1 more source

Business-as-usual and fantasy planning - an analysis of equity within climate adaptation planning for sanitation in Nairobi. [PDF]

PLoS One
Hyde-Smith LK, Ddiba D, Dickin S, Kiogora D, Mdee AL, Reinfelder V, Roelich KE, Evans B.   +7 more
europepmc   +1 more source