Results 181 to 190 of about 879,580 (295)

How can climate adaptation policy enhance urban climate resilience? Empirical evidence from China. [PDF]

PLoS One
Yin A, Liu Z.
europepmc   +1 more source

XIAP Stabilizes DDRGK1 to Promote ER‐Phagy and Protects Against Noise‐Induced Hearing Loss

Advanced Science, EarlyView.
Mechanism of GAS‐mediated protection against noise‐induced hearing loss (NIHL). Noise exposure activates the ATF4/eIF2α axis, downregulating XIAP and promoting DDRGK1 degradation, thereby inhibiting ER‐phagy and leading to hair cell (HC) death. GAS treatment rescues XIAP and DDRGK1 expression, reactivating ER‐phagy to mitigate HC loss, synaptic damage,
Lin Yan, Yuhua Zhang, Jiawei Du, Yongjun Zhu, Wei Cao, Yongjie Wei, Han Wu, Shiyu Qiu, Shiyi Pan, Lian Chen, Pingping Liang, Renjie Chai, Jianming Yang, Qiaojun Fang   +13 more
wiley   +1 more source

Molecular signatures and machine learning driven stress biomarkers for rainbow trout aquaculture and climate adaptation. [PDF]

Sci Rep
Ali A, Ali Y, Raymo G, Dalei A, Salem M.
europepmc   +1 more source

Climate adaptation strategies

A+BE: Architecture and the Built Environment, 2016
The previous chapter is an almost theoretical approach to study thermal comfort effects. The increasing complexity from an open field to a single building and finally a combination of various vegetation types gives insight in the relative effects of changes in the urban environment on thermal comfort.
openaire   +1 more source

Genomics Insights Into High‐Latitude Adaptation of Tibetan Macaques

Advanced Science, EarlyView.
Tibetan macaques exhibit unique adaptations to cold, high‐latitude environments, including shortened tails and enhanced fat storage. Genomic analyses reveal a species‐specific TBX6 mutation linked to tail reduction and selection on lipid metabolism genes.
Rusong Zhang, Ying Hu, Yang Teng, Jiwei Qi, Yangzhen Ciren, Lin Zhang, Qiao Du, Wencai Xu, Liang Zhou, Zhenxin Fan, Jinchuan Xing, Ming Li, Jing Li   +12 more
wiley   +1 more source

Climate Adaptation and Genetic Differentiation in the Mosquito Species Culex tarsalis. [PDF]

Genome Biol Evol
Liao Y, Islam T, Noorai R, Streich J, Saski C, Cohnstaedt LW, Cooper EA.   +6 more
europepmc   +1 more source

Versatile CRISPR‐Cas Tools for Gene Regulation in Zebrafish via an Enhanced Q Binary System

Advanced Science, EarlyView.
This study introduces CRISPR‐Q, a transgenic CRISPR‐Cas system leveraging the QFvpr/QUAS binary expression platform in zebrafish. CRISPR‐Q overcomes previous challenges in achieving stable and efficient gene regulation. By enabling precise spatiotemporal control of transcript knockdown (CRISPR‐QKD) and gene activation (CRISPR‐Qa), it provides a ...
Miaoyuan Shi, Weiqi Ge, Changheng Li, Bin Liu, Xiaoyi Deng, Chengjie Liu, Meijun Zheng, Pu Zhang, Lei Li, Ying Guo, Yunqi Han, Yu Yang, Yanxun V. Yu, Youngnam N. Jin   +13 more
wiley   +1 more source

Participatory approaches to climate adaptation, resilience, and mitigation: A systematic review. [PDF]

Ambio
Parsons M, Godden NJ, Henrique KP, Tschakert P, Gonda N, Atkins E, Steen K, Crease RP.   +7 more
europepmc   +1 more source

Adaptation critical in changing climate [PDF]

, 2012
O'Brien, Geoff
core  

Navigating the Ethereal Tightrope: The Nanogenerator Manipulates Neurons for Immune Equilibrium

Advanced Science, EarlyView.
This review explores how nanogenerators modulate neuroimmune responses, offering innovative strategies for treating neurological disorders. By interfacing with neural pathways, they enable precise control of immune activity, especially via vagus nerve stimulation.
Jia Du, Rui Deng, Ya Wu, Hong‐Xia Ren, Zong‐Hong Lin, Yang‐Bao Miao   +5 more
wiley   +1 more source