Results 231 to 240 of about 5,789,121 (307)

Global trends in the burden of malaria: mapping the prevalence, incidence and mortality of <i>Plasmodium falciparum</i> and <i>Plasmodium vivax</i> in the era of climate change and emerging drug resistance. [PDF]

BMJ Glob Health
Abbasi E.
europepmc   +1 more source

A Chiral Virus‐Like Nanoplatform That Broadly Mediates Antibiotic Delivery to the Brain for Bacterial Meningitis Therapy

Advanced Science, EarlyView.
Chiral virus‐mimicking mesoporous silica nanostructures (CVSNs) efficiently transport diverse antibiotics across the blood–brain barrier (BBB) into brain parenchyma and cerebrospinal fluid. By enhancing delivery to microglia and astrocytes, CVSNs improve antibiotic bioavailability and therapeutic efficacy against both Gram‐negative and Gram‐positive ...
Qianqian Xu, Xuting Zheng, Huinan Tong, Ying Liu, Xiaoxi Fan, Miao Xu, Ziyan Zhang, Li Zhang, Mingyan Liu, Ting Du, Heran Li, Guojun Liu   +11 more
wiley   +1 more source

Sustained resilience as a unifying property of cities and the built environment. [PDF]

NPJ Urban Sustain
Mitoulis SA, Kopiika N, Di Bari R, Argyroudis S.   +3 more
europepmc   +1 more source

Biobased Boston Ivy‐Inspired Cryogel Integrating Radiative Cooling and Phase Change Energy Storage for Adaptive Thermal Regulation

Advanced Science, EarlyView.
A bionic cryogel containing phase‐change materials that provides daytime radiative cooling and nighttime heat release is developed to promote environmentally sustainable and comfortable housing and living environments with reduced building energy demand.
Sining Huang, Zhiguo Li, Yang Liu, Chengyu Wang, Yi Lu, Erlantz Lizundia, Siqi Huan   +6 more
wiley   +1 more source

Sustainable Mite Management in Apple Orchards Under Climatic Stress: Ecological Trade-Offs and System Challenges. [PDF]

Insects
Karabayeva AA, Kopzhassarov BK, Sarseyeva GB, Ziyayeva GK, Nogerbek AD, Baubekova AK.   +5 more
europepmc   +1 more source

Municipal Climate Adaptation in Sweden: An analysis of Fiscal Capacity and Climate Exposure

Climate adaptation has become an increasingly important responsibility for Swedish municipalities, yet adaptation progress varies considerably between local governments. This study explores how fiscal capacity and climate exposure relate to variation in climate adaptation progress among four smaller Swedish municipalities: Boden, Arvika, Bollnäs, and ...
openaire   +1 more source

Chrysanthemum Morifolium–Derived Nanovesicles Reduce Lactate‐Associated Histone Lactylation and Modulate Microglia‐Mediated Neuroinflammation in Sepsis‐Associated Encephalopathy

Advanced Science, EarlyView.
When used to treat sepsis‐associated encephalopathy, Chrysanthemum morifolium–derived nanovesicles can inhibit the H3K18la/NF‐κB axis to regulate microglia‐mediated neuroinflammation. ABSTRACT Sepsis‐associated encephalopathy (SAE)—a complication of the central nervous system in patients with sepsis—markedly diminishes cognitive functions and is linked
Kaiqiang Li, Xuling Luo, Xiaoting Zhang, Chengwen He, Wei Xu, Aibo Xu, Shushan Hua, Liping Wang, Liang Ma, Ke Hao, Youmin Ying, Zhen Wang   +11 more
wiley   +1 more source

NSUN3‐Associated m5C Modification of tRF5‐GlyTCC Suppresses Colorectal Cancer Progression via RPL23‐Linked Nucleolar Stress and p53‐Associated Autophagy and Enhances 5‐FU Sensitivity

Advanced Science, EarlyView.
This study identifies that NSUN3‐mediated m5C modification stabilizes tRF5‐GlyTCC, linking ribosomal homeostasis, nucleolar stress responses, and p53 signaling changes. This regulatory axis suppresses colorectal cancer and enhances chemotherapy response to 5‐FU, positioning tRF5‐GlyTCC as a potential therapeutic target for improving drug sensitivity in
Xinhui Lv, Can Tang, Feiyang Song, Yu Wu, Yafang Chen, Sicong Liu, Ziwen Yuan, Guihua Wang, Xudong Wang   +8 more
wiley   +1 more source

Vulnerability assessment to tropical cyclones in the North Caribbean Coast of Nicaragua (1988-2022). [PDF]

PLoS One
Muñoz-Requene L, Sánchez-Zamora P, Gallardo-Cobos R.   +2 more
europepmc   +1 more source