Results 11 to 20 of about 16,968,314 (408)
Multiple sclerosis clinical decision support system based on projection to reference datasets
Annals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 1863-1873, December 2022., 2022 Abstract Objective Multiple sclerosis (MS) is a multifactorial disease with increasingly complicated management. Our objective is to use on‐demand computational power to address the challenges of dynamically managing MS. Methods A phase 3 clinical trial data (NCT00906399) were used to contextualize the medication efficacy of peg‐interferon beta‐1a vs ...
Chadia Ed‐driouch +13 more
wiley +1 more source
A transient inflammatory response contributes to oxaliplatin neurotoxicity in mice
Annals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 1985-1998, December 2022., 2022 Abstract Objectives Peripheral neuropathy is a relevant dose‐limiting adverse event that can affect up to 90% of oncologic patients with colorectal cancer receiving oxaliplatin treatment. The severity of neurotoxicity often leads to dose reduction or even premature cessation of chemotherapy.
Aina Calls +9 more
wiley +1 more source
Changing the intellectual climate [PDF]
Nature Climate Change, 2014 Calls for more broad-based, integrated, useful knowledge now abound in the world of global environmental change science. They evidence many scientists' desire to help humanity confront the momentous biophysical implications of its own actions. But they also reveal a limited conception of social science and virtually ignore the humanities.
Paige West +23 more
openaire +9 more sources
A review of the global climate change impacts, adaptation, and sustainable mitigation measures
Environmental science and pollution research international, 2022 Climate change is a long-lasting change in the weather arrays across tropics to polls. It is a global threat that has embarked on to put stress on various sectors.
Kashif Abbass +5 more
semanticscholar +1 more source
CLASSIC v1.0: the open-source community successor to the Canadian Land Surface Scheme (CLASS) and the Canadian Terrestrial Ecosystem Model (CTEM) – Part 1: Model framework and site-level performance [PDF]
Geoscientific Model Development, 2020 Recent reports by the Global Carbon Project highlight large uncertainties around land surface processes such as land use change, strength of CO2 fertilization, nutrient limitation and supply, and response to variability in climate.
J. R. Melton +6 more
doaj +1 more source
Canadian Journal of Remote Sensing, 2023 Arctic amplification has many impacts on sea-ice extent, thickness, and flux. It becomes critical to monitor sea-ice conditions at finer spatio-temporal resolution.
Benoit Montpetit +3 more
doaj +1 more source
Advanced Engineering Materials, EarlyView., 2023 This study aims to explore the feasibility of using a structure inspired by the features of horsetail and human spine as the potential helmet liner, targeting at mitigation of acceleration‐induced injuries. A parametric study is conducted to investigate the effect of individual geometrical variables in the design, indicating its capability to reduce ...
Bing Leng +3 more
wiley +1 more source
Coral endosymbiont growth is enhanced by metabolic interactions with bacteria
Nature Communications, 2023 Bacteria are key contributors to microalgae resource acquisition, competitive performance, and functional diversity, but their potential metabolic interactions with coral microalgal endosymbionts (Symbiodiniaceae) have been largely overlooked.
Jennifer L. Matthews +10 more
doaj +1 more source
Learning and climate change [PDF]
Climate Policy, 2006 Learning – i.e., the acquisition of new information that leads to changes in our assessment of uncertainty – plays a prominent role in the international climate policy debate. For example, the view that we should postpone actions until we know more continues to be influential.
Michael Oppenheimer +18 more
openaire +5 more sources
Estimation of Canada's methane emissions: inverse modelling analysis using the Environment and Climate Change Canada (ECCC) measurement network [PDF]
Atmospheric Chemistry and PhysicsCanada has major sources of atmospheric methane (CH4), with the world's second-largest boreal wetland and the world's fourth-largest natural gas production. However, Canada's CH4 emissions remain uncertain among estimates.
M. Ishizawa +6 more
doaj +1 more source