Results 251 to 260 of about 3,277,034 (311)

Intracellular Aβ42 Sequestration by a Serine Protease Mitigates Neurotoxicity in a Drosophila Alzheimer's Disease Model

open access: yesAdvanced Science, EarlyView.
Emerging evidence suggests that intraneuronal Aβ accumulation represents an early pathogenic event in Alzheimer's disease (AD). Using Drosophila AD model, this study shows that a nonsecreted serine protease Yip7 physically interacts with Aβ. This causes intraneuronal Aβ accumulation but surprisingly reduces the associated neurotoxicity, arguing that ...
Jingyun Su   +4 more
wiley   +1 more source

4‐Hydroxybenzyl Alcohol Mitigates Hyperlipidemia‐Associated Depression by Inhibiting Neuroinflammation via the NKIRAS2/NF‐κB Pathway

open access: yesAdvanced Science, EarlyView.
4‐HBA upregulates NKIRAS2 levels, inhibiting the activation of the NF‐κB pathway and subsequently reducing the levels of neuroinflammatory markers. This modulation helps restore normal mood and behavior in hyperlipidemic conditions, providing a potential therapeutic strategy for managing hyperlipidemia‐associated depression.
Ying Zhang   +7 more
wiley   +1 more source

Precipitation observing network gaps limit climate change impact assessment. [PDF]

open access: yesNature
Su J   +24 more
europepmc   +1 more source

A call to action: impact of climate change on TB and recovery after TB. [PDF]

open access: yesIJTLD Open
Mabhula A   +4 more
europepmc   +1 more source

Changement climatique, agriculture et sécurité alimentaire [PDF]

open access: yes, 2012
CGIAR Research Program on Climate Change, Agriculture and Food Security
core  

Climate Change and Reproductive Health.

open access: yesEndocr Rev
Fernandez ACG   +6 more
europepmc   +1 more source

Impact of climate change on spontaneous abortion: a systematic review and meta-analysis. [PDF]

open access: yesFront Glob Womens Health
Angaw DA   +4 more
europepmc   +1 more source

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