Results 261 to 270 of about 17,557,131 (355)

Climate change effects on hydrologic processes and water quality in the Connecticut River watershed. [PDF]

PeerJ
Parry H, Randhir TO.
europepmc   +1 more source

On Climate Change: Climate Change: the Science

Ecology, Economy and Society–the INSEE Journal, 2018
openaire   +3 more sources

mGluR5 in ECCCK to BLA Circuit Modulates Depressive‐Like Phenotypes through CCK Signaling

Advanced Science, EarlyView.
Dysregulation of mGluR5 and CCK signaling contributes to major depressive disorder, yet circuit‐level mechanisms remain unclear. Here, the ECCCK→BLA pathway is identified as a critical regulator of affective behavior. mGluR5 modulates synaptic function and CCK signaling within this circuit, controlling stress susceptibility and depressive‐like states ...
Muhammad Asim, Huajie Wang, Gao Qianqian, Abdul Waris, Jufang He   +4 more
wiley   +1 more source

Climate change and citrus nutrition: mechanisms, nutrient imbalances, and inclusive management. [PDF]

Front Plant Sci
Srivastava AK, Barlas NT, Wu QS, Raveh E, Brunetto G, Vashisth T, Mousavi SM, Acharya UK.   +7 more
europepmc   +1 more source

Astrocytic Phenotypic Switching in Posterior Piriform Cortex Orchestrates Bone Cancer Pain–Depression Comorbidity via Purinergic–Noradrenergic Signaling

Advanced Science, EarlyView.
Bone cancer pain and depression share a common origin: astrocytic A2‐to‐A1 transition in the posterior piriform cortex. This phenotypic shift disrupts the ATP–adenosine–A2AR–norepinephrine axis, simultaneously driving nociceptive and affective dysfunction.
Jiang‐Ping Liu, Jun‐Han Zhang, Zhi‐Xuan Tan, Wei‐Bing Yan, Ya‐Ru Yuan, Yao Liu, Bing‐Di Wei, Meng‐Qi Ding, Zhuo‐Min Fu, Ying Liu, An‐Qi Wang, Lin Ma, Yong‐Hong Li, Er‐Qing Chai, Chao‐Jun Wei   +14 more
wiley   +1 more source

Climate Change Perceptual Awareness, Climate-Related Anxiety, and Perceived Impacts of Climate Change Among University Students in Jordan: Findings from a Multi-University Cross-Sectional Study. [PDF]

Int J Environ Res Public Health
Al-Tammemi AB, Al-Maqableh HO, Aljarrah M, Alhallaq SA, AlKhyat AWA, Hasan H, Al Tamimi D, Alnatsheh MT, Hina HR, Qudah EM, Joudeh B, Abusido MI, Banat M, Omari A, Suboh DJ, AlAhmad SH, Al-Ghawanmeh R, Zayed DK, Momani S, Khatatbeh H, Ayasreh I, Athamneh RY, Khatatbeh M, Barakat M, Abdulla F, Al-Qudah M, Mukattash TL.   +26 more
europepmc   +1 more source

VDAC1 Upregulation Induces Hyperexcitability of Nociceptive Sensory Neurons Via Enhanced Mitochondrial Atp Efflux in Neuropathic Pain

Advanced Science, EarlyView.
The mechanism diagram of VDAC1 mediating neuronal excitability and neuropathic pain. Briefly, VDAC1 is expressed in DRG neurons and is upregulated following CCI‐induced neuropathic pain. This upregulation enhances ATP transport from mitochondria to the cytoplasm in sensory neurons, leading to increased neuronal excitability and pain behavior.
Fengrun Sun, Ning Yu, Liang Yu, Xiaofen Tian, Yujia Ma, Yikuan Xie, Tao Wang, Chao Ma   +7 more
wiley   +1 more source

Climate Change and Hydropower Impacts on Habitat Suitability of Endangered Schizothoracinae Fishes in the Qinghai-Xizang Plateau. [PDF]

Ecol Evol
Zhou Y, Zheng Q, Liu F, Han Z, Liu H, Wang X, Gao H, Pan H, Li Y, Ma J, Zhou C, Li Y, Liu H.   +12 more
europepmc   +1 more source

MEOX1 Coordinates Autocrine‐Paracrine Programs via SPHK1/S1P to Promote Lymph Node Metastasis in Ovarian Cancer

Advanced Science, EarlyView.
In ovarian cancer, MEOX1 activates the SPHK1/S1P pathway to promote both tumor progression and tumor–stroma crosstalk. MEOX1‐dependent signaling drives CAF activation, enhances VEGF‐C expression, and stimulates lymphangiogenesis, ultimately facilitating lymph node metastasis.
Jiajia Li, Xiuling Zhi, Qianhan Lin, Yating Sun, Yihua Sun, Zulimire Abudousalamu, Mengyang Xue, Chang Zheng, Xiaotian Li, Liangqing Yao, Mo Chen   +10 more
wiley   +1 more source

Global Research and Action Agenda for Climate Change and Mental Health

Lawrance E, Vay JNL, Ajlouni Y, Ali S, Yongabi KA, Aruta JJB, Bailey M, Belkin G, Clayton S, Collins P, Santos Md, Eissa M, Omrani OE, Faciolince M, Greaves N, Guinto R, Hayes K, Hill K, Jennings N, Lekwa H, Maharaj S, Massazza A, Minor K, Misha F, Modi T, Nasar S, Otto F, Pressburger L, Qudah M, Ridout M, Trisos C, Vercammen A, Watson D, Wray B, Wright S, Zeitz L.   +35 more
europepmc   +1 more source