Results 141 to 150 of about 446,988 (280)

ADAPTATION AND MITIGATION: TRADE-OFFS IN SUBSTANCE AND METHODS [PDF]

open access: yes
climate change, adaptation ...
Richard S.J. Tol
core  

Tri–Band and Dual–Response Smart Windows With Asymmetric Mid–Infrared Emissivity for Year–Round Energy Conservation

open access: yesAdvanced Science, EarlyView.
Our promising smart window exhibits exceptional optical properties, enabling the indoor temperature reduction of 12°C during summer and delivering the annual energy savings of 14.2%–24.4% across mid–to–low latitudes. ABSTRACT Building energy consumption accounts for 20%–40% of global energy usage, with windows among the least energy–efficient ...
Cheng Wang   +11 more
wiley   +1 more source

URBAN INDIA AND CLIMATE CHANGE: MITIGATION STRATEGIES TOWARDS INCLUSIVE GROWTH [PDF]

open access: yes
Climate change has been emerged as a major challenge for the sustainable human settlement. The recent studies have established scientific evidences for climate change.
Mack Joong CHOI, Sohail AHMAD
core  

XIAP Stabilizes DDRGK1 to Promote ER‐Phagy and Protects Against Noise‐Induced Hearing Loss

open access: yesAdvanced Science, EarlyView.
Mechanism of GAS‐mediated protection against noise‐induced hearing loss (NIHL). Noise exposure activates the ATF4/eIF2α axis, downregulating XIAP and promoting DDRGK1 degradation, thereby inhibiting ER‐phagy and leading to hair cell (HC) death. GAS treatment rescues XIAP and DDRGK1 expression, reactivating ER‐phagy to mitigate HC loss, synaptic damage,
Lin Yan   +13 more
wiley   +1 more source

Adapting and Mitigating to Climate Change: Balancing the Choice under Uncertainty [PDF]

open access: yes
Nowadays, as stressed by important strategic documents like for instance the 2009 EU White Paper on Adaptation or the recent 2009 “Copenhagen Accord”, it is amply recognized that both mitigation and adaptation strategies are necessary to combat climate ...
Chen Chen, Francesco Bosello
core  

Versatile CRISPR‐Cas Tools for Gene Regulation in Zebrafish via an Enhanced Q Binary System

open access: yesAdvanced Science, EarlyView.
This study introduces CRISPR‐Q, a transgenic CRISPR‐Cas system leveraging the QFvpr/QUAS binary expression platform in zebrafish. CRISPR‐Q overcomes previous challenges in achieving stable and efficient gene regulation. By enabling precise spatiotemporal control of transcript knockdown (CRISPR‐QKD) and gene activation (CRISPR‐Qa), it provides a ...
Miaoyuan Shi   +13 more
wiley   +1 more source

Adaptation, Mitigation and Innovation: A Comprehensive Approach to Climate Policy [PDF]

open access: yes
The ultimate question that most interests policy makers is how to reduce the climate change vulnerability of socio-economic systems in the most cost-effective manner. Extended literature has investigated the different dimensions of mitigation strategies,
Carlo Carraro   +3 more
core  

The Mitochondrial Guardian α‐Amyrin Mitigates Alzheimer's Disease Pathology via Modulation of the DLK‐SARM1‐ULK1 Axis

open access: yesAdvanced Science, EarlyView.
Dietary habits play a key role in chronic diseases, and higher annual consumption of fruit and vegetable may lower risk of dementia. Artificial intelligence predicts the lipid‐like compound α‐Amyrin (αA) from plants with edible peels as a drug candidate against Alzheimer's disease.
Shu‐Qin Cao   +36 more
wiley   +1 more source

Adaptation, Mitigation and Risk-Taking in Climate Policy [PDF]

open access: yes
The future consequences of climate change are highly uncertain. Today, the exact size of possible future damages are widely unknown. Governments try to cope with these risks by investing in mitigation and adaptation measures.
Heike Auerswald   +2 more
core  

MicroRNA‐375‐3p Targets Fatty Acid Synthase and Relish to Regulate Energy Allocation During Pupal Metamorphosis and Starvation

open access: yesAdvanced Science, EarlyView.
During pupal metamorphosis and starvation, elevated 20‐hydroxyecdysone (20E) and suppressed insulin trigger Forkhead box O (FOXO) nuclear translocation, enhancing miR‐375‐3p expression. This downregulates fatty acid synthase (FASN) and Relish, promoting lipid breakdown for energy while prioritizing antioxidant responses over immune functions to support
Peng Chen   +10 more
wiley   +1 more source

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