Results 211 to 220 of about 446,988 (280)

TGM2 Aggravates Acute Pancreatitis by Impairing Macrophage Efferocytosis Through Inhibition of the STAT6–GAS6 Axis

Advanced Science, EarlyView.
This study shows TGM2 is upregulated in AP, impairing macrophage efferocytosis by inhibiting the STAT6–GAS6 axis. The lactoferrin‐modified, ROS‐responsive LF‐LNP@si‐TGM2 targets pancreatic macrophages, silences TGM2, restores the axis, and alleviates AP.
Xuxu Liu, Zhiwei Du, Liyi Wang, Zhihong Xie, Ziang Meng, Yi Zheng, Heming Wang, Yuanhang He, Dongbo Xue   +8 more
wiley   +1 more source

Trade-Offs and Synergies Between Climate Change Mitigation, Biodiversity Preservation, and Agro-Economic Development Across Future Land-Use Scenarios in Brazil. [PDF]

Glob Chang Biol
Gérard TMR, Norder SJ, Verstegen JA, Doelman JC, Dekker SC, van der Hilst F.   +5 more
europepmc   +1 more source

H2S‐Releasing Aspirin Nanoparticles Alleviate Endometriosis and Associated Anxiety

Advanced Science, EarlyView.
Albumin nanoparticles loaded with an H2S‐releasing aspirin derivative (ACS14) hitchhiking neutrophils after intraperitoneal injection and preferentially accumulate in endometriosis lesions in mice. The treatment suppresses lesion growth by regulating PI3K/Akt and reduces inflammation by inhibiting NF‐κB.
Mengni Zhou, Renbin Dou, Rong Wu, Yunyu Xu, Ying Wang, Peng Wang, Jinfu Li, Pengcheng Lu, Yu Mao, Jieying Qian, Yunjiao Zhang, Jiqian Zhang, Shasha Zhu   +12 more
wiley   +1 more source

Temperate forests can deliver future wood demand and climate-change mitigation dependent on afforestation and circularity. [PDF]

Nat Commun
Forster EJ, Styles D, Healey JR.
europepmc   +1 more source

Hierarchical MXene/ZnO Nanorods: WO3/CNT Trilayer Coatings on Cotton for High‐Performance Multifunctional Wearable Fabrics

Advanced Science, EarlyView.
xx xx. ABSTRACT Fabric‐based wearable electronics are gaining increasing attention owing to their flexibility, breathability, biocompatibility, and seamless integration into clothing. However, most existing studies rely primarily on metallic or carbon‐based conductive materials.
Thirumalaisamy Suryaprabha, Chunghyeon Choi, Sujith Lal, Min‐Young Seo, Tae‐Wook Kim, Ergang Wang, Byungil Hwang   +6 more
wiley   +1 more source

Leveraging explainable AI to predict soil respiration sensitivity and its drivers for climate change mitigation. [PDF]

Sci Rep
Novielli P, Magarelli M, Romano D, Di Bitonto P, Stellacci AM, Monaco A, Amoroso N, Bellotti R, Tangaro S.   +8 more
europepmc   +1 more source

TRIM40 Drives Pathological Cardiac Hypertrophy and Heart Failure via Ubiquitination of PKN2

Advanced Science, EarlyView.
This study identifies the E3 ligase TRIM40 as a key driver of pathological cardiac hypertrophy. TRIM40 binds PKN2 via its B‐box domain and, through its C29‐dependent catalytic activity, mediates K63‐linked ubiquitination of PKN2. This modification enhances PKN2 phosphorylation at Ser815, thereby driving hypertrophy.
Risheng Zhao, Xiaoli Cui, Huizhu Du, Zhuoqun Wang, Chang Liu, Linxin Zhang, Jianing Qi, Di Yang, Hui Yu, Shuang Yan, Wei Liu, Haiming Sun, Mengyang Wang   +12 more
wiley   +1 more source

Making climate change mitigation policy less regressive in the residential sector

Kulkarni S, Hof A, Daioglou V, Vuuren Dv.   +3 more
europepmc   +1 more source

Readiness for climate change mitigation among anesthesiologists : A before and after study at three German university hospitals. [PDF]

Anaesthesiologie
Baumann AAW, Grüßer L, Dölker T, Lehmann F, Kowark A, Ziemann S, Obert DP, Schuler J, Sander M, Schneider G, Schulz CM, Schneider F, Conway N.   +12 more
europepmc   +1 more source

Rapid Steam‐Assisted Temperature Swing Adsorption for Direct Air Capture Using a Rotary Adsorber

Advanced Science, EarlyView.
This study presents a direct air capture (DAC) device based on a steam‐regeneration rotary adsorber for high‐purity CO2. Testing of the prototype demonstrates its capability for continuous and stable carbon capture with the potential to achieve ton‐scale.
Junye Wu, Yunhao Chen, Kuihua Wang, Yingjie Huo, Yanlin Chen, Quanwen Pan, Tianshu Ge   +6 more
wiley   +1 more source