Results 61 to 70 of about 2,354,068 (222)

Targeting the KCNC3‐Dependent Anterior Insular‐Lateral Orbitofrontal Cortex Glutamatergic Circuit Attenuates Post‐Traumatic Anxiety

open access: yesAdvanced Science, EarlyView.
Frontal lobe traumatic brain injury is associated with hyperactivity of an insular–orbitofrontal circuit in both patients and mice. By combination of integrating functional imaging, cell‐type–specific circuit manipulation, single‐cell transcriptomics, and whole‐cell recordings, this work identifies the downregulation of the potassium channel KCNC3 in ...
Meng‐Ge Li   +10 more
wiley   +1 more source

Basic Emotions, Complex Emotions, Machiavellian Emotions [PDF]

open access: yes, 2002
The current state of knowledge in psychology, cognitive neuroscience and behavioral ecology allows a fairly robust characterization of at least some, so-called basic emotions - short-lived emotional responses with homologues in other vertebrates ...
Griffiths, Paul E.
core  

VlPAG/DRN Microglia Drive Neuropathic Pain‐Induced Depression via a Defined Neuroimmune Axis

open access: yesAdvanced Science, EarlyView.
Peripheral nerve injury (SNI) induces neuropathic pain, activates midbrain microglia, and triggers an NLRP3–IL‐1β–dependent inflammatory cascade. IL‐1β signals through IL‐1R1 on vlPAG/DRN VGLUT2+ neurons (vlPAG/DRNGlu), inducing hyperexcitability and driving the vlPAG/DRNGlu→BNSTGABA circuit to produce the affective component of neuropathic pain ...
Jing Yang   +7 more
wiley   +1 more source

Targeting CXCR2 in Nociceptive Sensory Neurons Offers Novel Therapeutic Potentials for Postoperative Pain

open access: yesAdvanced Science, EarlyView.
Tissue incision induces CXCL5 release, which activates neuronal CXCR2 on incision‐innervating sensory neurons. Neuronal CXCR2 couples with TRPA1 to drive mechanical pain and engages p38 MAPK signaling to upregulate TRPV1 and promote heat pain. Targeted Cxcr2 knockdown relieves incisional pain while preserving CXCR2‐dependent neutrophil responses ...
Yushuang Pan   +10 more
wiley   +1 more source

“This is what I love and this is what’s at risk”: how climate grief reveals values that inspire climate action

open access: yesEcology and Society
Climate grief, including pain and sadness related to climate change and its impacts on life and society, is increasingly recognized in global discourse about climate change and mental health.
Stephanie Olsen   +3 more
doaj   +1 more source

What Really Drives Agri‐Environment‐Climate Measures' Adoption? Mandatory Requirements, Behavioral Traits, and Structural Factors in the CAP Green Architecture

open access: yesApplied Economic Perspectives and Policy, EarlyView.
ABSTRACT To increase farmer adoption of green practices, the EU Common Agricultural Policy includes both mandatory (conditionality) and voluntary instruments (eco‐schemes–ECS– and more demanding, multi‐annual agri‐environment‐climate measures –AECM–). Building on the experiment of Barreiro‐Hurle et al.
L. Sanchez‐Mata   +4 more
wiley   +1 more source

Climate of Emotions: A Pilot Study on Transforming Climate Emotions into Resilience

open access: yes
This paper presents a theoretically grounded psychological intervention and a pilot study examining its impact during NYC Climate Week. The study investigated the effects of emotional intelligence (EI) skill development on climate emotions, specifically climate isolation, climate anxiety, climate powerlessness, and climate enthusiasm, during a three ...
Patty Freedman   +4 more
openaire   +1 more source

Promoting Healthier Drinking: Evidence From a Vignette Experiment on Contextual and Informational Drivers of Dealcoholized Wine Choices

open access: yesApplied Economic Perspectives and Policy, EarlyView.
ABSTRACT Growing demand for healthier beverages is driving innovation in the wine sector, with dealcoholized wine emerging as a promising alternative. However, little is known about the contextual conditions under which consumers would choose dealcoholized wine, particularly in countries with strong wine traditions. To fill this gap, this work examines
Giovanna Piracci   +4 more
wiley   +1 more source

Climate Anxiety as Anticolonial Activism

open access: yesAustralian Journal of Environmental Education
There is now an abundance of literature pointing to the relationship between the escalating global impacts of climate change and the adverse effects of irreversible ecological destruction on the emotional worlds of children and young people ...
Kathryn Morog
doaj   +1 more source

The Role of Emotion in Climate Change Communication

open access: yesEnvironmental Communication
Extreme weather events are becoming increasingly frequent and severe worldwide. Emotional messages might be persuasive in communicating this information, but it remains unclear whether message efficacy depends more on emotional content or delivery. In a pre-registered experiment (N = 3,463), participants were randomly assigned to listen to one of seven
Laura Thomas-Walters   +5 more
openaire   +1 more source

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