Results 121 to 130 of about 98,562 (311)
Adipocyte‐Derived Leptolin Enhances Energy Expenditure and Prevents Obesity
Advanced Science, EarlyView.We identified a novel adipokine, which we named leptolin. In humans, leptolin levels in white adipose tissue were positively correlated with exercise and negatively associated with body mass index. We observed elevated leptolin in serum from athletes and lower leptolin in serum from obese individuals.
Jiarui Liu +17 more
wiley +1 more source
Changes in precipitation amounts and extremes across Xinjiang (northwest China) and their connection to climate indices. [PDF]
PeerJ, 2021 Hu W, Yao J, He Q, Chen J.
europepmc +1 more source
Advanced Science, EarlyView.Fibronectin 1 (FN1)‐expressing subicular subpopulations encode novel object preference and selectively govern retrieval of novel object recognition (NOR) via affecting excitability of entorhinal‐projecting circuit through large conductance Ca2+‐activated potassium (BK) channel. ABSTRACT Novel object recognition (NOR), referring to the cognitive ability
Fan Fei +15 more
wiley +1 more source
When will unusual heat waves become normal in a warming Africa?
Environmental Research Letters, 2016 Africa is one of the most vulnerable continents to climate change. In the upcoming decades the occurrence of longer, hotter and more frequent heat waves could have a strong impact on human mortality and crop production.
Simone Russo +3 more
doaj +1 more source
Plant Pathogens as Indicators of Climate Change
, 2016 The response of plant disease to weather variables such as temperature and precipitation is well known and has been the basis for disease forecasting models used in decision-making by farmers and policy makers. Thus, plant disease risk can readily shift under climate change.
Garrett, K. A. +5 more
openaire +3 more sources
The effectiveness of the Paris Agreement in achieving its global temperature goal relies on countries adopting ambitious mitigation targets and introducing corresponding measures. But do countries adopt such corresponding climate policies?
Baker, Jack +3 more
core +1 more source
, 2006 A 44-yr climatology of spring Asian dust aerosol emission. column loading. deposition, trans-Pacific transport routes, and budgets during 1960-2003 was simulated with the Northern Aerosol Regional Climate Model (NARCM).
Zhao, TL +13 more
core +1 more source
Targeting the PDK1/c‐Myc/SOX10 Signaling in Oligodendrocytes Alleviates Neuropathic Pain
Advanced Science, EarlyView.This work reveals that oligodendrocyte homeostasis, mediated by PDK1, is a critical determinant of neuropathic pain (NPP) pathogenesis. Disruption of PDK1 in oligodendrocytes impairs SOX10‐dependent myelination programs through c‐Myc accumulation, leading to disrupted myelination and the pathophysiology of NPP.
Pingping Qiao +7 more
wiley +1 more source
Advanced Science, EarlyView.ABSTRACT Brown and beige adipocytes dissipate energy as heat, yet effective strategies to enhance their mitochondrial efficiency remain limited. Here, we identify Agnuside (AGN) as a selective stabilizer of the complex I assembly factor NDUFAF6. AGN directly binds cytosolic NDUFAF6, suppresses its ubiquitination, prolongs its half‐life, and facilitates
Qingwen Zhao +7 more
wiley +1 more source