Results 141 to 150 of about 98,562 (311)

Sex‐Specific Regulation of Glycemic Homeostasis by Theabrownin from Pu‐erh Tea

Advanced Science, EarlyView.
Pu‐erh tea's key component, theabrownin (TB), lowers blood glucose in a sex‐specific manner. In females, estrogen boosts intestinal MUC2 production, which dramatically enhances TB's ability to inhibit the carbohydrate‐digesting enzyme α‐glucosidase.
Yang Li, Junliang Kuang, Dan Zheng, Jieyi Wang, Kun Ge, Chun Qu, Xiaojiao Zheng, Zhenxing Ren, Fengjie Huang, Mingliang Zhao, Yimin Sun, Huiheng Zhang, Keke Ding, Xixi Xia, Yajun Tang, Lu Liu, Jian Zhou, Fei Gao, Xiaohui Ma, Yongquan Xu, Guoxiang Xie, Aihua Zhao, Wei Jia   +22 more
wiley   +1 more source

A Toolkit for Targeted Neuromodulation of Striatal Direct Pathway Neurons Rescues Parkinsonian Motor Deficits in Mice

Advanced Science, EarlyView.
An adeno‐associated virus (AAV) toolkit enables selective anatomical and functional targeting of striatal D1‐MSNs through retrograde transduction. Enhanced capsids and engineered enhancers drive robust transgene expression across murine and primate models.
Zexuan Hong, Yujing Zhang, Junjiao Zhang, Hanhe Liu, Qiwei Liu, Yanglei Li, Lixin Yang, Lixia Li, Zhongjie Liu, Zhen Yuan, Zhonghua Lu, Yefei Chen, Yuantao Li, Yuwu Jiang, Taian Liu   +14 more
wiley   +1 more source

The changing physical and ecological meanings of North Pacific Ocean climate indices. [PDF]

Proc Natl Acad Sci U S A, 2020
Litzow MA, Hunsicker ME, Bond NA, Burke BJ, Cunningham CJ, Gosselin JL, Norton EL, Ward EJ, Zador SG.   +8 more
europepmc   +1 more source

Icariin Enhances the Enzymatic Activity of N‐acetylgalactosaminidase to Augment Akkermansia Abundance in Gut Microbiota for Improved PD‐1 Blockade Efficacy in Tumor Suppression

Advanced Science, EarlyView.
Icariin promoted the growth of Akk by enhancing the activity of N‐acetylgalactosaminidase (Amuc_0920), which enhanced mucin utilization and provided a favorable nutrient environment for bacterial growth. This icariin‐mediated enrichment of Akk further reshaped the tumor microenvironment and promoted CD8+ T cell infiltration, ultimately synergizing with
Shuangying Qiao, Liu Yang, Haibang Hao, Qiuxia Ding, Feng Ding, Zheng Chen, Jinfang Zhang, Yun He, Meng Li, Jun Xu, Chao Wang, Aiping Lu, Fangfei Li   +12 more
wiley   +1 more source

Climate Variability and Atlantic Surface Gravity Wave Variability Based on Reanalysis Data

Journal of Marine Science and Engineering
Wave climate variability, including seasonal cycles, long-term trends, and interannual anomalies of wave parameters, was investigated across five latitudinal sectors using ERA5 reanalysis data from 1980 to 2023.
Yuri Onça Prestes, Alex Costa da Silva, André Lanfer Marquez, Gabriel D’annunzio Gomes Junior, Fabrice Hernandez   +4 more
doaj   +1 more source

Corals and Reef‐Dwelling Fish Regulate Carbon Storage and Cycling Processes in Coral Reef Ecosystems

Advanced Science, EarlyView.
Coral reefs are biodiversity hotspots, yet their role in carbon storage and cycling remains poorly understood. Using field surveys and modeling in the South China Sea, we reveal the overlooked potential of carbon storage in reef ecosystems and how reef fish, corals, and surface sediment jointly shape reef carbon reservoirs.
Yiting Chen, Wenliang Zhou, Lan Qiu, Han Lai, Mingpan Huang, Qian Li, Wen Yu, Pei‐Yuan Qian, Fuwen Wei   +8 more
wiley   +1 more source

A Flexible Global Warming Index for Use in an Integrated Approach to Climate Change Assessment [PDF]

Global Warming Potential (GWP) is an index used to measure the relative accumulated radiative effect of a tonne of greenhouse gas (GHG) compared to that of a 'reference' gas (CO2).
Claudia Kemfert, Truong P. Truong
core  

Mapping the “Supply–Demand–Flow” of Ecosystem Services for Ecosystem Management in China

Advanced Science, EarlyView.
This study develops a “supply–demand–flow” framework clarifies how ecosystem services move between regions by distinguishing potential and actual supply and demand. Using integrated biophysical–socioeconomic modeling, nine services in China were mapped.
Yikun Zhang, Yadong Yang, Yongsheng Wang, Guirui Yu   +3 more
wiley   +1 more source

Drought forecasting with regionalization of climate variables and generalized linear model

Meteorological Applications
Spring drought forecasting is essential in South Korea for managing water resources reliably and cultivating agricultural products efficiently, as seasonal rainfall difference often drives water shortage during spring.
Taesam Lee, Yejin Kong, Joo‐Heon Lee, Chang‐Hee Won   +3 more
doaj   +1 more source

LANDSURF - Climate Indices for Africa

The dataset contains a wide range of climatological and agrometeorological indices of Africa for 1981-2100. The index calculation is based on global and regional climate models from CMIP5 and CORDEX-CORE, respectively, and covers the period 1981-2100 ...
Abel, Daniel, Ziegler, Katrin
core   +1 more source