Results 101 to 110 of about 108,876 (300)
Advanced Science, EarlyView.Fibronectin 1 (FN1)‐expressing subicular subpopulations encode novel object preference and selectively govern retrieval of novel object recognition (NOR) via affecting excitability of entorhinal‐projecting circuit through large conductance Ca2+‐activated potassium (BK) channel. ABSTRACT Novel object recognition (NOR), referring to the cognitive ability
Fan Fei +15 more
wiley +1 more source
Measuring safety climate in health care
, 2006 A systematic literature review was undertaken to study sample and questionnaire design characteristics (source, no of items, scale type), construct validity (content validity, factor structure and internal reliability, concurrent validity), within group ...
Burns, C. +4 more
core +1 more source
Targeting the PDK1/c‐Myc/SOX10 Signaling in Oligodendrocytes Alleviates Neuropathic Pain
Advanced Science, EarlyView.This work reveals that oligodendrocyte homeostasis, mediated by PDK1, is a critical determinant of neuropathic pain (NPP) pathogenesis. Disruption of PDK1 in oligodendrocytes impairs SOX10‐dependent myelination programs through c‐Myc accumulation, leading to disrupted myelination and the pathophysiology of NPP.
Pingping Qiao +7 more
wiley +1 more source
Environmental Research LettersSince Crutzen’s (2006 Clim. Change 77 211–20) call for research into stratospheric aerosol geoengineering (SAG), a form of solar radiation modification, the field of SAG research has witnessed substantial growth.
Anu Xavier +2 more
doaj +1 more source
Testing the climate intervention potential of ocean afforestation using the Great Atlantic Sargassum Belt. [PDF]
Nat Commun, 2021 Bach LT +5 more
europepmc +1 more source
Advanced Science, EarlyView.ABSTRACT Brown and beige adipocytes dissipate energy as heat, yet effective strategies to enhance their mitochondrial efficiency remain limited. Here, we identify Agnuside (AGN) as a selective stabilizer of the complex I assembly factor NDUFAF6. AGN directly binds cytosolic NDUFAF6, suppresses its ubiquitination, prolongs its half‐life, and facilitates
Qingwen Zhao +7 more
wiley +1 more source
Sulfur Exposure for Airplane Passengers From Stratospheric Aerosol Injection
Geophysical Research LettersInjection of sulfur dioxide to create a stratospheric sulfate aerosol cloud is the most studied method of climate intervention. It has been suggested that airplanes be used at high latitudes to create such a cloud at lower altitudes. Commercial airplanes
Alan Robock +3 more
doaj +1 more source
Assessing the financial vulnerability to climate-related natural hazards [PDF]
National governments are key actors in managing the impacts of extreme weather events, yet many highly exposed developing countries -- faced with exhausted tax bases, high levels of indebtedness, and limited donor assistance -- have been unable to raise ...
Mechler, Reinhard +4 more
core
Persuasive Data Visualization and Interactive Narrative for Climate Change Awareness
, 2022 Climate change is a global phenomenon that affects every living being on our planet. We have been observing drastic changes to our climate since the last few decades.
Adib, Ashfaq A Zamil
core
Dissecting the Ecological Structure of Health and Disease in the Global Gut Microbiome
Advanced Science, EarlyView.We introduce Wiredancer, a framework that identifies three continuous ecological factors of the gut microbiota. These factors exhibit distinct patterns across health and disease, jointly capturing disrupted ecological stability and offering a new perspective for precision diagnostics and therapeutic strategies.
Baoyuan Zhu +19 more
wiley +1 more source