Results 151 to 160 of about 4,005,912 (283)

Intranasal Delivery of Gallium–Quercetin Nanoparticles for Multi‐Target Ferroptosis Inhibition in Parkinson's Disease

Advanced Science, EarlyView.
Leveraging the chemical similarity between Ga3+ and Fe3+ as well as the antioxidant properties of quercetin, gallium–quercetin nanoparticles (GQNPs) were prepared to integrate iron homeostasis regulation, oxidative stress suppression, and mitochondrial protection for multi‐target ferroptosis inhibition in Parkinson's Disease.
Keyang Xu, Dandan Kou, Xiao Xiao, Bingbing Bai, Caide Liu, Mengyao Wu, Yadan Shi, Mengdan Xu, Xiaoyi Cao, Haodi Qi, Shuhua Wu, Jianfeng Zeng, Mingyuan Gao   +12 more
wiley   +1 more source

Maternal Exercise Rescues Embryonic Osteogenesis Impaired due to POLG Mutation Through a Potential Apelin‐ATF4 Axis

Advanced Science, EarlyView.
Maternal exercise (ME) increases apelin abundance across maternal and fetal tissues and is associated with improved fetal osteogenesis under POLG mutation‐induced mitochondrial dysfunction. Apelin‐APJ signaling is linked to enhanced mitochondrial function, Akt phosphorylation, and ATF4‐RUNX2 association, supporting coordinated fetal bone remodeling ...
Song Ah Chae, Ryan C. Riddle, Zhihua Jiang, Chaeyoung Shin, Min Du, Jun Seok Son   +5 more
wiley   +1 more source

Exploring global climate intervention experiments: sociotechnical promises, innovation dynamics, and perceived co-impacts across 20 projects and pilots. [PDF]

Sustain Sci
Sovacool BK, Baum CM, Fritz L, Low S.
europepmc   +1 more source

Advancing Energy Efficiency in Smart Windows via Dual‐Responsive Electro‐Thermochromism

Advanced Science, EarlyView.
A durable and stable quasi‐solid‐state electro‐thermal dual‐responsive photothermal regulation device has been employed in advanced energy‐efficient smart windows. The devised device not only incorporates a thermochromic hydrogel characterized by high ionic conductivity, high optical transmittance, and a low LCST, but also comprises an electrochromic ...
Tongyu Chen, Bing Xu, Guolong Zhou, Wenting Wu, Bingkun Huang, Xiaohui Tang, William W. Yu, Pooi See Lee, Wu Zhang, Zhongyang Wang, Jingwei Chen   +10 more
wiley   +1 more source

Rectifying misinformation on the climate intervention potential of ocean afforestation. [PDF]

Nat Commun
Smetacek V, Fernández-Méndez M, Pausch F, Wu J.   +3 more
europepmc   +1 more source

m6A‐Driven Pexophagy Triggers Placental Ferroptosis to Impair Fetal Growth Upon Environmental Stress

Advanced Science, EarlyView.
Prenatal environmental stress exposure promotes m6A modification to drive PEX2‐dependent pexophagy, thereby causing placental ferroptosis and FGR. ABSTRACT The role and underlying mechanisms of placental ferroptosis in fetal growth restriction (FGR) induced by environmental stress remain poorly understood.
Xin‐Xin Zhang, Ye‐Xin Luo, Cheng‐Fang Sun, Rui Pan, Yu‐Xi Wu, Zhi Yuan, Xin‐Run Wang, Xu‐Dong Zhang, Lan‐Lan Wu, Xiang‐Yu Yao, Zhan‐Dong Song, Wei Chang, Tian Wei, Pan‐Yuan Cai, Tian‐Ci Zhang, Yong‐Wei Xiong, De‐Xiang Xu, Hua Wang, Hua‐Long Zhu   +18 more
wiley   +1 more source

Reply to: Rectifying misinformation on the climate intervention potential of ocean afforestation. [PDF]

Nat Commun
Bach LT, Tamsitt V, Gower J, Hurd CL, Raven JA, Visch W, Boyd PW.   +6 more
europepmc   +1 more source

The interplay of climate, intervention and imported cases as determinants of the 2014 dengue outbreak in Guangzhou. [PDF]

PLoS Negl Trop Dis, 2017
Cheng Q, Jing Q, Spear RC, Marshall JM, Yang Z, Gong P.   +5 more
europepmc   +1 more source

Enhancing climate change communication: Strategies for profiling and targeting Australian interpretive communities

, 2013
This research aimed to provide practical information about how to design communications on climate change adaptation and target these to the Australian population.
Reser, Joseph, Hine, Donald, Hine, Donald W, Phillips, Wendy J, Ellul, Michelle, Reser, Joseph P, Watt, Susan, Cooksey, Ray W, Marks, Anthony, Nunn, Patrick, Watt, Susan E, Phillips, Wendy, Cooksey, Ray   +12 more
core  

Blood Cell‐Camouflaged Liquid Metal Nanoconjugates Orchestrate Treg Depletion and STING‐Amplified Photothermal Immunity for Metastatic Triple‐Negative Breast Cancer Therapy

Advanced Science, EarlyView.
Whole‐blood biomimetic engineering transforms liquid metal nanoparticles into a tripartite immunotherapeutic platform that orchestrates regulatory T‐cell depletion, photothermal‐induced immunogenic cell death, and activation of the stimulator of interferon genes pathway.
Nina Sang, Eijiro Miyako
wiley   +1 more source