Results 31 to 40 of about 108,876 (300)

Creating a climate for food security: the business, people & landscapes in food production [PDF]

, 2013
Balancing human and environmental needs is urgent where food security and sustainability are under pressure from population increases and changing climates.
Nazrul Islam, Nasir Uddin, Angela Wardell-Johnson   +2 more
core  

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Identifying Climate Impacts From Different Stratospheric Aerosol Injection Strategies in UKESM1

Earth's Future
Stratospheric Aerosol Injection (SAI) is a proposed method of climate intervention aiming to reduce the impacts of human‐induced global warming by reflecting a portion of incoming solar radiation.
Alice F. Wells, Matthew Henry, Ewa M. Bednarz, Douglas G. MacMartin, Andy Jones, Mohit Dalvi, James M. Haywood   +6 more
doaj   +1 more source

Decision-making for climate change adaptation: A systems thinking approach [PDF]

, 2013
The impacts of climate change are exacerbated by inefficient adaptation and mitigation decision making, due to the complexity of the decision-making environment. As a consequence, there is no single approach to planning and decision making.
Kambiz Maani, Maani, Kambiz
core  

Tropical–North Pacific Climate Linkages over the Past Four Centuries [PDF]

, 2005
Analyses of instrumental data demonstrate robust linkages between decadal-scale North Pacific and tropical Indo-Pacific climatic variability. These linkages encompass common regime shifts, including the noteworthy 1976 transition in Pacific climate ...
Cook, E., Wiles, G., Villalba, R., Tudhope, A., Villalba, R, Cole, J., D'Arrigo, R, D'Arrigo, R., Tudhope, A, Wiles, G, Linsley, B, Cook, E, Linsley, B., Deser, C, Wilson, R., Cole, J, Deser, C., Wilson, Rob   +17 more
core   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Stratospheric Aerosol Injection to Stabilize Northern Hemisphere Terrestrial Permafrost Under the ARISE‐SAI‐1.5 Scenario

Earth's Future
Permafrost, or ground that is continuously frozen for at least 2 years, contains vast stores of organic soil carbon. Stratospheric aerosol injection (SAI) may prevent tipping points that lead to widespread permafrost thaw and carbon release by cooling ...
A. L. Morrison, E. A. Barnes, J. W. Hurrell   +2 more
doaj   +1 more source

Adaptor of last resort? An economic perspective on the government’s role in adaptation to climate change [PDF]

, 2013
 Individuals and societies have always adapted to change, whether catastrophic or slow onset. Over the last two centuries, however, governments have significantly extended their role as ultimate social manager of risk.
Leo Dobes, Patrick Doupe, Frank Jotzo
core  

Advancing climate change adaptation and climate risk understanding through intervention research: case studies from Brazil and Australia

, 2016
This chapter provides a reflection on the role of intervention research in aiding climate change adaptation by improving both adaptive capacity and the understanding of climate risks.
Gabriela Marques Di Giulio, Darryl Low Choy, Choy, DL, Silvia Serrao-Neumann, Di Giulio, Gabriela Marques, Ferreira, Lucia Costa, Lucia Costa Ferreira, Ferreira, LC, Serrao-Neumann, S, Serrao-Neumann, Silvia, Low Choy, Darryl, Di Giulio, GM   +11 more
core   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source