Results 31 to 40 of about 4,005,912 (283)

Climate and Airborne Pollutants [PDF]

open access: yes, 2008
Pamphlet describing climate projections based on emission scenarios for long-lived and short-lived radiatively active gases and ...
Climate Change Science Program (U.S.)
core  

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

Stratospheric Aerosol Injection to Stabilize Northern Hemisphere Terrestrial Permafrost Under the ARISE‐SAI‐1.5 Scenario

open access: yesEarth's Future
Permafrost, or ground that is continuously frozen for at least 2 years, contains vast stores of organic soil carbon. Stratospheric aerosol injection (SAI) may prevent tipping points that lead to widespread permafrost thaw and carbon release by cooling ...
A. L. Morrison   +2 more
doaj   +1 more source

Projected changes to Arctic shipping routes after stratospheric aerosol deployment in the ARISE-SAI scenarios

open access: yesFrontiers in Climate
IntroductionRapid reductions in Arctic sea ice in response to warming have led to increased interest in using the Arctic Ocean for commercial shipping. As the world warms, however, different strategies are being considered to stabilize or reduce surface ...
Ariel L. Morrison   +3 more
doaj   +1 more source

Thirsty country: climate change and drought in Australia [PDF]

open access: yes, 2015
This report argues that climate change is likely making drought worse in the southeast and southwest of Australia, which are some of our most populous regions. Introduction Drought has deeply affected Australia throughout its history.
Climate Council
core  

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

open access: yesFEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen   +8 more
wiley   +1 more source

Natural Variability Can Mask Forced Permafrost Response to Stratospheric Aerosol Injection in the ARISE‐SAI‐1.5 Simulations

open access: yesEarth's Future
Stratospheric aerosol injection (SAI) has been proposed as a potential method for mitigating risks and impacts associated with anthropogenic climate change. One such risk is widespread permafrost thaw and associated carbon release.
A. L. Morrison   +2 more
doaj   +1 more source

Midwestern Regional Climate Center [PDF]

open access: yes, 2001
Made available in DSpace on 2016-11-14T22:36:27Z (GMT). No. of bitstreams: 2 ISWSIEM2001-01.pdf: 146176 bytes, checksum: 791a8da476fabb8bec8c3d10ae0a0993 (MD5) license.txt: 3973 bytes, checksum: 6c1c5beee39794d995a5ff442f5bd9ab (MD5) Previous issue ...
Midwestern Regional Climate Center
core  

IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo

open access: yesFEBS Open Bio, EarlyView.
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley   +1 more source

A multiple needs framework for climate change anxiety interventions.

open access: yesAmerican Psychologist, 2021
Climate change anxiety is a growing problem for individual well-being the world over. However, psychological interventions to address climate change anxiety may have unintended effects on outcomes other than individual well-being, such as group cohesion and pro-environmental behavior.
William John Bingley   +8 more
openaire   +5 more sources

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