Results 31 to 40 of about 90,766 (258)

Change in Mental Health and Resilience in Childhood Cancer Survivors After Attending a Person‐Centred State‐of‐the‐Art Late Effects Clinic—on Behalf of the PanCareFollowUp Consortium

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Person‐centred follow‐up care based on evidence‐based clinical practice guidelines and providing individualised information should help to inform and reassure survivors about their medical and psychosocial situation and provide treatment and support where needed.
Gisela Michel, Mieke Rijken, Marietta Kokla, Charlotte Sleurs, Jurgen Lemiere, Line Elmerdahl Frederiksen, Luzius Mader, Cecilia Follin, Sara Oberti, Jeanette Falck Winther, Selina R. van den Oever, Leontien C. M. Kremer, Helena J. H. van der Pal, Peter Spreeuwenberg, Eline Bouwman, Jeroen te Dorsthorst, Samira Essiaf, Elizabeth A. M. (Lieke) Feijen, Hannah Gsell, Riccardo Haupt, Maria van Helvoirt, Rosella P. M. G. Hermens, Lars Hjorth, Tomas Kepak, Katerina Kepakova, Anita Kienesberger, Monica Muraca, Marleen Renard, Carina Schneider, Roderick Skinner, Anne Uyttebroeck, Deveny Vanrusselt, Sabine Verschueren, Jacqueline Loonen, Saskia M. F. Pluijm, Katharina Roser, the PanCareFollowUp consortium   +36 more
wiley   +1 more source

Natural Variability Can Mask Forced Permafrost Response to Stratospheric Aerosol Injection in the ARISE‐SAI‐1.5 Simulations

Earth's Future
Stratospheric aerosol injection (SAI) has been proposed as a potential method for mitigating risks and impacts associated with anthropogenic climate change. One such risk is widespread permafrost thaw and associated carbon release.
A. L. Morrison, E. A. Barnes, J. W. Hurrell   +2 more
doaj   +1 more source

A multiple needs framework for climate change anxiety interventions.

American Psychologist, 2021
Climate change anxiety is a growing problem for individual well-being the world over. However, psychological interventions to address climate change anxiety may have unintended effects on outcomes other than individual well-being, such as group cohesion and pro-environmental behavior.
William John Bingley, Anh Tran, Candice Boyd, Kari Gibson, Elise Katherine Kalokerinos, Peter Koval, Yoshihisa Kashima, Dianna McDonald, Katharine Helen Greenaway   +8 more
openaire   +5 more sources

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Stratospheric aerosol climate intervention could reduce crop nutritional value

Environmental Research Letters
The deliberate addition of sulfur dioxide in the stratosphere to form reflective sulfate aerosols, reflect sunlight, and reduce surface temperatures is increasingly being considered as an option for minimizing the impacts of climate change. This strategy
Brendan Clark, Alan Robock, Lili Xia, Sam S Rabin, Jose R Guarin, Jonas Jägermeyr   +5 more
doaj   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Impacts on Indian Agriculture Due To Stratospheric Aerosol Intervention Using Agroclimatic Indices

Earth's Future
Climate change poses significant threats to global agriculture, impacting food quantity, quality, and safety. The world is far from meeting crucial climate targets, prompting the exploration of alternative strategies such as stratospheric aerosol ...
Nina Grant, Alan Robock, Lili Xia, Jyoti Singh, Brendan Clark   +4 more
doaj   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Maize Yield Changes Under Sulfate Aerosol Climate Intervention Using Three Global Gridded Crop Models

Earth's Future
As the severity of climate change and its associated impacts continue to worsen, schemes for artificially cooling surface temperatures via planetary albedo modification are being studied.
Brendan Clark, Alan Robock, Lili Xia, Sam S. Rabin, Jose R. Guarin, Gerrit Hoogenboom, Jonas Jägermeyr   +6 more
doaj   +1 more source