Results 41 to 50 of about 824,470 (298)

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

Climate models

open access: yesComptes Rendus. Mécanique
The first climate models have emerged in the 60s and have been continuously developed since then. They have progressively included the representation of all the climate system components: the atmosphere, the ocean, the cryosphere and the biosphere. Inside each component, they have also been enriched by the representation of more processes with the aim ...
Koskinen, Rami, Pättiniemi, Ilkka
  +6 more sources

The News You Choose: News Media Preferences Amplify Views on Climate Change [PDF]

open access: yes, 2018
How do choices among information sources reinforce political differences on topics such as climate change? Environmental sociologists have observed large-scale and long-term impacts from news media and think-tank reports, while experimental science ...
Bolin, Jessica L, Hamilton, Lawrence C.
core   +2 more sources

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

open access: yesFEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao   +3 more
wiley   +1 more source

The global aerosol–climate model ECHAM6.3–HAM2.3 – Part 2: Cloud evaluation, aerosol radiative forcing, and climate sensitivity [PDF]

open access: yesGeoscientific Model Development, 2019
The global aerosol–climate model ECHAM6.3–HAM2.3 (E63H23) as well as the previous model versions ECHAM5.5–HAM2.0 (E55H20) and ECHAM6.1–HAM2.2 (E61H22) are evaluated using global observational datasets for clouds and precipitation.
D. Neubauer   +10 more
doaj   +1 more source

Why human connection is the true metric of research success

open access: yesFEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan   +3 more
wiley   +1 more source

Deglacial variability of South China hydroclimate heavily contributed by autumn rainfall

open access: yesNature Communications, 2021
Deglacial hydroclimate in South China is perennially debated. New modeling experiments reveal that regional hydroclimate was strongly influenced by rainfall during the transition between the East Asian summer monsoon and winter monsoon, forced by climate
Chengfei He   +8 more
doaj   +1 more source

A framework for modeling uncertainty in regional climate change [PDF]

open access: yes, 2015
In this study, we present a new modeling framework and a large ensemble of climate projections to investigate the uncertainty in regional climate change over the United States (US) associated with four dimensions of uncertainty.
Gao, X   +4 more
core  

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

open access: yesFEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho   +4 more
wiley   +1 more source

An evaluation of the regional distribution and wet deposition of secondary inorganic aerosols and their gaseous precursors in IFS-COMPO preparatory to cycle 49R1 [PDF]

open access: yesGeoscientific Model Development
Secondary Inorganic Aerosol (SIA) makes up a considerable fraction of the total particulate matter exposure and, thus, is an important product from any forecasting system of atmospheric composition and air quality.
J. E. Williams   +4 more
doaj   +1 more source

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