Results 41 to 50 of about 4,806,651 (288)
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Ice Monitoring in Swiss Lakes from Optical Satellites and Webcams Using Machine Learning
Continuous observation of climate indicators, such as trends in lake freezing, is important to understand the dynamics of the local and global climate system.
Manu Tom +5 more
doaj +1 more source
This research provides bihourly temperature and relative humidity data from ten measuring locations in eight caves from one of the largest contiguous arid karst areas in the world, the Nullarbor Plain in south Australia.
Matej Lipar, Mateja Ferk
doaj +1 more source
Climate change 2015: growing risks, critical choices [PDF]
This latest Climate Council report provides an update of climate change science, impacts and risks. This report draws from the massive body of evidence that human activities - primarily from the burning of coal, oil and gas - are driving dramatic changes
Climate Council
core
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu +9 more
wiley +1 more source
Short-lived Climate Pollutants [PDF]
Report summarizing the policy-relevant findings of the Arctic Monitoring and Assessment Programme' 2015 assessments of short-lived climate pollutants (Methane, Black carbon, and Ozone)
Arctic Monitoring and Assessment Programme
core
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David +12 more
wiley +1 more source
Thirsty country: climate change and drought in Australia [PDF]
This report argues that climate change is likely making drought worse in the southeast and southwest of Australia, which are some of our most populous regions. Introduction Drought has deeply affected Australia throughout its history.
Climate Council
core
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen +8 more
wiley +1 more source
INFORMATION TECHNOLOGY OF CLIMATE MONITORING
Context. Information monitoring technology is used to reduce information uncertainty about the regularity of air temperature changes during managing work in hard-to-reach places [1]. The task was to create a method for modelling one of the climatic indicators, air temperature, in the given territories in the information monitoring technology structure.
M. V. Talakh, S. V. Holub, I. B. Turkin
openaire +4 more sources

