Results 181 to 190 of about 2,906,823 (288)

Psychological capital and farmer families' quality of life under the climate variability conditions. [PDF]

Sci Rep
Mohammadi-Mehr S, Hayati D, Karami E.
europepmc   +1 more source

Identification and Characterization of an In Silico Designed Membrane‐Active Peptide with Antiviral Properties

Advanced Science, EarlyView.
An evolutionary molecular dynamics platform is used to design P1.6, a membrane‐active peptide that senses lipid packing defects in viral envelopes. P1.6 adopts a stabilized α‐helical structure upon membrane contact, disrupts virus‐like liposomes, and damages HIV‐1 particles.
Pascal von Maltitz, Niek van Hilten, Tatjana Weil, Thunchanok Thummaraj, Jeroen Methorst, Dennis Aschmann, Alexander Kros, Clarissa Read, Jasmina Gačanin, Herre Jelger Risselada, Jan Münch   +10 more
wiley   +1 more source

Regional restructuring in planktic foraminifera communities through Pliocene-early Pleistocene climate variability. [PDF]

Nat Commun
Larina E, Woodhouse A, Swain A, Lowery CM, Martindale RC, Myers CE.   +5 more
europepmc   +1 more source

Climate variability drives recent tree mortality in Europe

Global Change Biology, 2017
M. Neumann, V. Mues, A. Moreno, H. Hasenauer, R. Seidl   +4 more
semanticscholar   +1 more source

Paving the Way to Elucidate Hg's Role in Tumorigenesis

Advanced Science, EarlyView.
Tumorigenesis can result from diverse environmental carcinogens. Among them, mercury—a lifelong bioaccumulative Group 2B carcinogen—has tumorigenic potential that remains poorly understood due to confounding co‐exposures and limited organ‐specific data.
Shouying Li, Rong Zhong, Zhenyang Yu, Hualing Fu, Jin Chen, Jia Wei, Ningwei Zhao, Le Qu, Tiantian Li, Wenli Tang, Huan Zhong   +10 more
wiley   +1 more source

Lake pulses driven by glacier melting and climate variability. [PDF]

Sci Rep
Ai S, Shah SA, Cai Y, Ling J, Chu X, Wang S, Yang Y, Ouyang R, An J, Rack W.   +9 more
europepmc   +1 more source

Restriction of Individual Branched‐Chain Amino Acids has Distinct Effects on the Development and Progression of Alzheimer's Disease in 3xTg Mice

Advanced Science, EarlyView.
Protein restriction (PR) slows Alzheimer's disease (AD) in mice, and other benefits of PR are due to decreased branched‐chain amino acids (BCAAs). We show that restricting any BCAA has benefits, with sex‐ and BCAA‐specific impacts on pathology, molecular signaling, and cognition.
Reji Babygirija, Cara L. Green, Michelle M. Sonsalla, Izabelle Marie F. Le, Fan Xiao, Sarah Yandell, Mariah F. Calubag, Michaela E. Trautman, Anna Tobon, Ryan Matoska, Chung‐Yang Yeh, Charles I. Opara, Isaac Grunow, Diana Vertein, Sophia Schlorf, Bailey A. Knopf, Michael J. Rigby, David A. Harris, Mark P. Keller, Alan D. Attie, Luigi Puglielli, Cholsoon Jang, Dudley W. Lamming   +22 more
wiley   +1 more source

Climate variability and warming in Coastal Odisha: assessing interannual temperature trends and impacts. [PDF]

Sci Rep
Sethi B, Sahu SC, Gouda KC, Beuria R, Mallick MK, Samal SK, Panigrahi A, Pati A.   +7 more
europepmc   +1 more source

TTNPB Promotes Human Pluripotent Stem Cell‐to‐Neural Stem Cell Transition via Modulation of Chromatin Accessibility and the S‐(5′‐adenosyl)‐L‐homocysteine/Choline Metabolic Network

Advanced Science, EarlyView.
A retinoic acid receptor agonist, TTNPB, drives the efficient generation of advanced neural stem cells (ANSCs) from human pluripotent stem cells. TTNPB‐centered chromatin remodeling and metabolic reprogramming, promote neuroectoderm commitment. The resulting cells show robust neural potential and functional efficacy in a rat depression model.
Ruilin Du, Yudi Ren, Qiaoqiao Meng, Peng Wei, Ruyu Zhu, Junjie Bao, Ye Yang, Shuo Yan, Chaorong Yue, Xueying Zhu, Shuo Cao, Chunxia Hao, Wei Sun, Yongli Song, Xihe Li, Zhimin Wu, Siqin Bao, Yanglin Chen   +17 more
wiley   +1 more source

Climate variability and Germanic settlement dynamics in the Middle Danube region during the Roman Period (1st-4th Century CE). [PDF]

PLoS One
Vlach M, Komoróczy B, Torbenson MCA, Esper J, Brázdil R, Büntgen U, Semerádová D, Urban O, Balek J, Kolář T, Rybníček M, Trnka M.   +11 more
europepmc   +1 more source