Results 111 to 120 of about 534,585 (397)

Evaluation and modification of tumor cell isolation techniques from malignant effusions for rapid drug sensitivity testing

open access: yesMolecular Oncology, EarlyView.
Non‐small cell lung cancer targeted treatment is limited to a few known genetic alterations, with few alternatives in advanced treatment lines. To direct treatment decisions by drug sensitivity testing (DST), this study compared several methods for tumor cell isolation from malignant effusions, pointing to repeated CD45+ cell depletion for effective ...
Navit Mooshayef   +10 more
wiley   +1 more source

Median computation in graphs using consensus strategies [PDF]

open access: yes
Following the Majority Strategy in graphs, other consensus strategies, namely Plurality Strategy, Hill Climbing and Steepest Ascent Hill Climbing strategies on graphs are discussed as methods for the computation of median sets of profiles.
Balakrishnan, K.   +2 more
core   +1 more source

Alpine Climbs [PDF]

open access: yesThe Geographical Journal, 1915
n ...
F., D. W., Rey, Guido
openaire   +3 more sources

Real-Time Experimental Assessment of Hill Climbing MPPT Algorithm Enhanced by Estimating a Duty Cycle for PV System

open access: yesInternational Journal of Renewable Energy Research, 2019
Better functioning of maximum power point tracking (MPPT) can significantly increase the energy efficiency of photovoltaic systems. This process is provided by MPPT algorithms.
Nzoundja Fapi Claude Bertin   +4 more
semanticscholar   +1 more source

Cytomegalovirus infection is common in prostate cancer and antiviral therapies inhibit progression in disease models

open access: yesMolecular Oncology, EarlyView.
Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon   +13 more
wiley   +1 more source

Analisis Implementasi Standar Keselamatan dan Pemakaian Peralatan Panjat Tebing untuk Meningkatkan Keselamatan Kerja pada Kegiatan Sport Climbing (Studi pada Fpti Jawa Tengah) [PDF]

open access: yes, 2013
Broadly speaking, the climbing wall is divided into two: Climbing Natural and Artificial Climbing. Artificial Climbing identical with Sport Climbing or Climbing Achievement commandeered By FPTI (Indonesian Rock Climbing Federation).
Jayanti, M.Sc, dr. Siswi   +2 more
core  

High-temperature creep of single-crystal nickel-based superalloy : microstructural changes and effects of thermal cycling [PDF]

open access: yes, 2011
Creep tests were performed on MC2 single crystal superalloy at 950°C/200 MPa and 1150°C/80 MPa under isothermal and thermal cycling conditions with a tensile axis along the [0 0 1] direction. It was found that the thermal cycles strongly affect the creep
Bernard Viguier   +4 more
core   +3 more sources

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

Fossil climbing perch and associated plant megafossils indicate a warm and wet central Tibet during the late Oligocene

open access: yesScientific Reports, 2017
Understanding the Tibetan Plateau’s palaeogeography and palaeoenvironment is critical for reconstructing Asia’s climatic history; however, aspects of the plateau’s uplift history remain unclear.
Feixiang Wu   +4 more
semanticscholar   +1 more source

Olaparib synergy screen reveals Exemestane induces replication stress in triple‐negative breast cancer

open access: yesMolecular Oncology, EarlyView.
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh   +5 more
wiley   +1 more source

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