Results 121 to 130 of about 473,538 (324)

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

open access: yesFEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp   +13 more
wiley   +1 more source

Zoborg: On‐Demand Climbing Control for Cyborg Beetles

open access: yesAdvanced Science
Transitioning from horizontal surfaces to vertical walls is crucial for terrestrial robots to navigate complex environments. Replicating such impressive surface transitions in artificial insect‐scale robots has been particularly challenging.
Lachlan Fitzgerald   +5 more
doaj   +1 more source

Comparison of Finger Flexor Strength and Muscle Quality Between Climbers and Non-Climbers: Influence of Sex and Grip Type

open access: yesApplied Sciences
Climbing demands exceptional isometric finger flexor strength and neuromuscular efficiency. This study aimed to compare maximum isometric strength and muscle quality (MQ) between climbers and non-climbers and examine the influence of sex and specific ...
Diego González-Martín   +4 more
doaj   +1 more source

Wall Climbing Glass Cleaner Robot

open access: diamond, 2021
Manish Donode   +5 more
openalex   +1 more source

But What do I Wear? A Study of Women's Climbing Attire [PDF]

open access: yes
Mrs Henry Warwick-Coleman advises the lady climber on her attire in her 1859 publication, A Lady’s Tour Round Monte Rosa. She suggests ‘A lady’s dress is inconvenient for mountaineering’, continuing ‘even under the most careful management, and therefore ...
Evans, C. K.
core  

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

open access: yesFEBS Open Bio, EarlyView.
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang   +7 more
wiley   +1 more source

TMC4 localizes to multiple taste cell types in the mouse taste papillae

open access: yesFEBS Open Bio, EarlyView.
Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata   +6 more
wiley   +1 more source

Technique of competition activity of sportsmen specialized in the speed climbing [PDF]

open access: yesPedagogìka, Psihologìâ ta Mediko-bìologìčnì Problemi Fìzičnogo Vihovannâ ì Sportu, 2010
The data of the quantitative and qualitative analysis of engineering of competitive activity of sportsmen are indicated. Parities in frequency of use of various techniques (basic items) for rockclimbers of a various level are defined.
Shulga A.S.
doaj  

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

open access: yesFEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan   +6 more
wiley   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

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