Results 141 to 150 of about 534,585 (397)
Connected Learning Journeys in Music Production Education [PDF]
, 2019 The field of music production education is a challenging one, exploring multiple creative, technical and entrepreneurial disciplines, including music composition, performance electronics, acoustics, musicology, project management and psychology.
Hepworth-Sawyer, R. +3 more
core
Repeat Expansions in PLIN4 Cause Autosomal Dominant Vacuolar Myopathy With Sarcolemmal Features
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective We aim to describe and characterize two unrelated Spanish families suffering from an autosomal dominant autophagic vacuolar myopathy caused by repeat expansions in PLIN4. Methods We evaluated the clinical phenotype and muscle imaging, and performed a genetic workup that included exome sequencing, muscle RNAseq, and long‐read genome ...
Laura Llansó +17 more
wiley +1 more source
The Role of Climbing Exercises in Developing Balance Ability in Children
Applied SciencesThis study aims to analyze the possibility of developing balance ability, highlighting symmetries, asymmetries, and levels of proprioception, in children aged 11–13 from practicing indoor and outdoor climbing and bouldering/escalation exercises.
Monica Căsăneanu (Resmeriță) +8 more
doaj +1 more source
A Nonparametric Efficiency Analysis of Bean Producers from North and South Kivu [PDF]
The purpose of this research is to determine how technically efficient small-scale producers are in two provinces (North and South Kivu) in the Democratic of Republic (DR) of Congo at producing two different varieties of beans: bush and climbing beans ...
Dalton, Timothy J. +2 more
core +1 more source
Activation of NF‐κB Signaling by Optogenetic Clustering of IKKα and β
Advanced Biology, EarlyView.This study presents an optogenetic approach for graded clustering of eGFP‐fused proteins using an eGFP‐specific nanobody and engineered Cryptochrome 2 variants. The method enables potent, reversible activation of NF‐κB signaling via endogenous pathways, as confirmed by RNA sequencing. This versatile system provides a spatially and temporally controlled
Alexandra Anna Maria Fischer +8 more
wiley +1 more source
Targeting RAGE with Nanobodies for Molecular Imaging of Cancers and Alzheimer's Disease
Advanced Biology, EarlyView.RAGE‐specific nanobodies were isolated via phage display and characterized by ELISA, cell ELISA, and SPR. In vivo imaging in renal carcinoma and Alzheimer's disease mouse models demonstrated that NbF8, the highest‐affinity clone, selectively targeted RAGE‐overexpressing tumors and brain tissues, highlighting its potential as a molecular imaging agent ...
Guangfeng Liang +13 more
wiley +1 more source
Observations on Mr Darwin's Views of Climbing Plants [PDF]
, 1873 Thomas A. G. Balfour
openalex +1 more source
Rolling in the Higgs Model and Elliptic Functions
, 2012 Asymptotic methods in nonlinear dynamics are used to improve perturbation theory results in the oscillations regime. However, for some problems of nonlinear dynamics, particularly in the case of Higgs (Duffing) equation and the Friedmann cosmological ...
A. M. Zhuravskii +14 more
core +1 more source
Advanced Biology, EarlyView.Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi +4 more
wiley +1 more source