Results 151 to 160 of about 534,585 (397)

RhoA and Rac1 as Mechanotransduction Mediators in Colorectal Cancer

open access: yesAdvanced Biology, EarlyView.
Analysing RhoA and Rac1 protein levels in Colorectal cancer (CRC) samples under mechanical strain highlights their potential as diagnostic markers. Monitoring their activity could offer valuable insights into how cancer spreads, paving the way for new approaches to better understand and diagnose colorectal cancer.
Sharda Yadav   +5 more
wiley   +1 more source

The Problem of Adhesion Methods and Locomotion Mechanism Development for Wall-Climbing Robots

open access: yes, 2019
This review considers a problem in the development of mobile robot adhesion methods with vertical surfaces and the appropriate locomotion mechanism design.
Bykov, Nikita V., Vlasova, Nataly S.
core  

Changes in handgrip force and blood lactate as response to simulated climbing competition [PDF]

open access: yes, 2009
The aim of the study was to estimate post-competition changes in handgrip strength and blood lactate in climbers and relationships of the studied variables with declared climbing ability of the tested athletes.
E Hübner-Woźniak   +3 more
core  

LIN28B Promotes Cancer Cell Dissemination and Angiogenesis

open access: yesAdvanced Biology, EarlyView.
Children diagnosed with high‐risk neuroblastoma have a 5‐year event‐free survival rate of less than 50% and poor outcomes after recurrence. Deregulation of the LIN28B oncogene can be addressed in these patients. Upregulation of LIN28B is shown to support the metastatic cascade.
Diana Corallo   +8 more
wiley   +1 more source

Articulated elastic-loop roving vehicles [PDF]

open access: yes, 1973
Prototype vehicle features exceptional obstacle-negotiating and slope-climbing capabilities plus high propulsive efficiency. Concept should interest designers of polar or ocean-bottom research vehicles.
Chang, C. J., Trautwein, W.
core   +1 more source

Inhibition of Glutamine Metabolism Attenuates Tumor Progression Through Remodeling of the Macrophage Immune Microenvironment

open access: yesAdvanced Biology, EarlyView.
The prodrug strategy used in this study offers new promise for cancer metabolism‐based therapies. JHU083, a prodrug that, when cleaved by protease in the tumor microenvironment, yields the glutamine antagonist DON. JHU083 inhibits tumor growth by targeting glutamine‐addicted cancer cells and suppressing glutamine‐dependent M2 macrophages, leading to a ...
Tianhe Li   +10 more
wiley   +1 more source

Work hands and feet in motion on the vertical ladder into the prosthesis disabled lower limb [PDF]

open access: yesPedagogìka, Psihologìâ ta Mediko-bìologìčnì Problemi Fìzičnogo Vihovannâ ì Sportu, 2012
The influence of the conditions of ascent and descent on the stairs with disabilities is shown. The study involved 12 persons with lower limb prosthetic right or left foot.
Li Yugang, Ma Haozhe, Chen Jian, Xia Yu
doaj  

Modern mechanisms make manless Martian mission mobile: Spin-off spells stairclimbing self-sufficiency for earthbound handicapped [PDF]

open access: yes, 1975
Concepts were developed for three wheel chairs from progressively improving designs of a proposed unmanned roving vehicle for the surface exploration of Mars; as a spin-off, a concept for a stair-climbing wheel chair was generated.
Hassel, D. R.   +2 more
core   +1 more source

Novel Biologically Active Glass Fiber Functionalized Using Magnesium Phosphate Cement Promotes Bone and Vascular Regeneration

open access: yesAdvanced Biology, EarlyView.
In this study, a new type of bioactive glass fiber ‐based composite magnesium phosphate bone cement is prepared and verified that its mechanical strength and biological properties. In addition, the cement may have played a biologically active role in the Notch and HIF signaling pathways.
Yuzheng Lu   +12 more
wiley   +1 more source

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