Results 161 to 170 of about 534,585 (397)
Fecal Microbiota Transplantation Modulates Th17/Treg Balance via JAK/STAT Pathway in ARDS Rats
Fecal microbiota transplantation (FMT) alleviates lung and intestinal injury in lipopolysaccharide (LPS)‐induced acute respiratory distress syndrome (ARDS) in rats. This study demonstrates that FMT restores the balance between Th17 and Treg cells, inhibits the JAK/STAT pathway, and modulates cytokine levels, reducing inflammation and lung damage. These
Dongwei Zhang+8 more
wiley +1 more source
The max-min hill-climbing Bayesian network structure learning algorithm
I. Tsamardinos+2 more
semanticscholar +1 more source
This study develops a tissue‐engineered model of the atherosclerotic cap using human mesenchymal stromal cells (MSCs). After 2 weeks of culture to produce a collagenous matrix, a mineralizing medium induces microcalcifications over 4 weeks. These constructs, imaged with second harmonic generation microscopy, lead to reduced ultimate stress at rupture ...
Imke L. Jansen+4 more
wiley +1 more source
A detailed workflow for recombinant GALC production and characterization is presented to support enzyme replacement therapy for Krabbe disease. In vitro assays demonstrate that physiological GALC doses restore enzymatic activity and autophagic flux without affecting cell viability, whereas higher doses impair autophagy and reduce viability.
Ambra Del Grosso+5 more
wiley +1 more source
The novelty of this study showed that the injection of exosomes produced from ADMSCs in combination with Roflumilast poses a more favorable therapeutic outcome for CKD induced by Adriamycin, compared to therapy with exosomes or Roflumilast alone. Roflumilast and exosomes treatment lowered the expression of the apoptotic, fibrotic, and inflammatory ...
Mohamed Ali+5 more
wiley +1 more source
Assessing the Ecological Value: Monetizing Process Innovations in Tailored Forming
This article introduces a method for evaluating the sustainability of innovations, even with limited data. The method is illustrated through an analysis of the “Tailored Forming” technology, which explores the impact of sustainability on economic value added.
Jonas Schneider+4 more
wiley +1 more source
A Method for Solving Distributed Service Allocation Problems
We present a method for solving service allocation problems in which a set of services must be allocated to a set of agents so as to maximize a global utility.
Vidal, Jose M
core +1 more source
From Damage to Functionality: Remanufacturing of Thrust Roller Bearings by Tailored Forming
Herein, the wear and fatigue behavior of repaired bearing raceways with a new powder alloy is investigated using a FE8 test‐rig and an oscillating tribometer. The tests are compared with industrial manufactured bearings to evaluate the repair quality. The repair can extend the service life of the repaired bearing to that of a new bearing and improves ...
Felix Saure+3 more
wiley +1 more source