Results 61 to 70 of about 8,311 (253)

Damage and shade enhance climbing and promote associational resistance in a climbing plant [PDF]

Journal of Ecology, 2007
# Associational resistance occurs when one plant species gains protection from its consumers by association with a defended species. In semi-arid ecosystems of Chile, the perennial herb Convolvulus chilensis (Convolvulaceae) suffers heavy herbivory by small mammals when growing prostrate but plants seem to be protected when they are climbing onto ...
Gonzalez-Teuber, Marcia, Gianoli, Ernesto   +1 more
openaire   +5 more sources

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Sizing up competition with strigolactones: the case of pea plants

Plant Signaling & Behavior
Plants, though sessile, can detect and respond to their neighbors through chemical signals such as strigolactones (SLs). We investigated how SL synthesis and perception affect the climbing behavior of Pisum sativum by analyzing wild-type plants and two ...
Bianca Bonato, Tom Bennett, Emanuele Cannizzo, Sara Avesani, Silvia Guerra, Umberto Castiello   +5 more
doaj   +1 more source

Global diversification of a tropical plant growth form: environmental correlates and historical contingencies in climbing palms

Frontiers in Genetics, 2015
Tropical rain forests (TRF) are the most diverse terrestrial biome on Earth, but the diversification dynamics of their constituent growth forms remain largely unexplored.
Thomas L. P. Couvreur, Thomas L. P. Couvreur, W. Daniel Kissling, Fabien L. Condamine, Jens-Christian eSvenning, Nick P. Rowe, William J. Baker   +6 more
doaj   +1 more source

Leaf Mimicry in a Climbing Plant Protects against Herbivory [PDF]

Current Biology, 2014
Mimicry refers to adaptive similarity between a mimic organism and a model. Mimicry in animals is rather common, whereas documented cases in plants are rare, and the associated benefits are seldom elucidated [1, 2]. We show the occurrence of leaf mimicry in a climbing plant endemic to a temperate rainforest.
Gianoli, Ernesto, Carrasco-Urra, Fernando   +1 more
openaire   +4 more sources

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Convolvulaceae do Parque Nacional do Catimbau, Pernambuco, Brasil

Rodriguésia
Convolvulaceae é constituída por 58 gêneros e ca. 1880 espécies com distribuição cosmopolita, sendo mais frequente nos trópicos. No Brasil é representada por 19 gêneros e aproximadamente 370 espécies.
Geadelande Carolino Delgado Júnior, Maria Teresa Buril, Marccus Alves   +2 more
doaj   +1 more source