Results 141 to 150 of about 61,216 (299)

Naturally Occurring CodY Variants Alter Ligand Binding, DNA Target Affinity, and Virulence in Clostridioides difficile

Molecular Microbiology, EarlyView.
Single amino acid substitutions in the global regulator CodY can alter nutrient sensing and virulence regulation in Clostridioides difficile. We show that the CodY(Y146N) and CodY(V58A) variants display altered ligand binding and reduced promoter binding, leading to derepression of toxin regulatory pathways and increased virulence in vivo.
Md Kamrul Hasan, Sourav Roy, Revathi Govind   +2 more
wiley   +1 more source

Cutaneous Toxicities Associated With Amivantamab in Patients With Non‐Small Cell Lung Cancer: A Systematic Review

International Journal of Dermatology, EarlyView.
Ioannis‐Alexios Koumprentziotis, Aikaterini Bakella, Antonis Tsimpidakis, Alexander Stratigos, Vasiliki Nikolaou   +4 more
wiley   +1 more source

Is Fluorescence‐Guided Surgery Reliable for the Treatment of MRONJ? A Systematic Review and Meta‐Analysis

Oral Diseases, EarlyView.
ABSTRACT Background Identification of healthy bone margins is a critical step in the surgical resective treatment of medication‐related osteonecrosis of the jaw (MRONJ). Fluorescence‐guided surgery (FGS) has been proposed as a method to identify resection margins and improve clinical outcomes.
Paolo De Angelis, Alessandro Donato Tescione, Ivan Michele Aniceto, Cosimo Rupe, Gioele Gioco, Romeo Patini, Carlo Lajolo   +6 more
wiley   +1 more source

Clindamycin in dentistry.

, 1994
Although clindamycin is not the drug of first choice for the majority of orofacial infections, it has a definite place in dental therapeutics.
van der Bijl P.
core  

Is It Safe to Implant Prosthesis When Frozen Section Reports Positive During Joint Arthroplasty? A Retrospective Cohort Study

Orthopaedic Surgery, EarlyView.
This study demonstrated that it is improper to overinterpret isolated frozen section positivity. It may be safe to implant prosthesis in patients who had positive frozen sections but without other signs of infection. Surgeons opting for staged revisions solely based on neutrophil counts risk unnecessary morbidity, particularly in patients with ...
Chiyuan Ma, Pingan Lin, Lingyun Wu, Jieli Zhou, Jiaxuan Zou, Pengfei Hu, Lidong Wu, Haobo Wu   +7 more
wiley   +1 more source

Treatment Patterns in Pediatric Hidradenitis Suppurativa: Time to Treatment Initiation, Initial Treatment, and Time to Switching

Pediatric Dermatology, EarlyView.
ABSTRACT Background Hidradenitis suppurativa (HS) causes significant morbidity in children. Treatment patterns across sex, race, and ethnicity in pediatric HS have not been thoroughly evaluated. We aim to characterize treatment patterns in pediatric HS, including (1) time to treatment initiation, (2) first prescribed HS treatment, and (3) time to ...
Shaliz Aflatooni, Andrea Ure, Kimberly Smart, Julian A. Cortes, Gabriela Palma, Nicole Johnsen, Yvonne Nong, April W. Armstrong   +7 more
wiley   +1 more source

Association of Nasal and Inhalant Corticosteroids With Pediatric Perioral Dermatitis: A TriNetX Retrospective Cohort Study

Pediatric Dermatology, EarlyView.
ABSTRACT Although topical corticosteroids are known triggers in the development of perioral dermatitis (PD), investigation into inhalant and nasal corticosteroid preparations, commonly used to manage allergic rhinitis and asthma, remains limited to case series.
Taylor Merkle, Caitlyn Curley, Dylan Wambold, Basira Iginla, Erum N. Ilyas   +4 more
wiley   +1 more source

Niger data Inducible clindamycin resistance

Macrolide-induced resistance to clindamycin is a well-described mechanism leading to the misuse of clindamycin and hence to treatment failure. In this study, we determined the frequency and associated factors of inducible clindamycin resistance in Gram ...
Abdourahamane Yacouba (9140471)
core   +1 more source

The effects of far‐UVC irradiation on the presence and concentration of ESKAPEE pathogens on hospital surfaces: Study protocol for a multi‐site, double‐blinded randomized controlled trial in La Paz, Bolivia

Photochemistry and Photobiology, EarlyView.
The protocol of a multi‐site, double‐blinded, clustered randomized controlled trial (cRCT) with a binary outcome of the presence of viable presumptive ESKAPEE pathogens on surfaces in and around hospital sinks is to be implemented in two Bolivian hospitals.
Lindsay B. Saber, Melani Rojas, Darcy M. Anderson, Deverick J. Anderson, Holger Claus, Ryan Cronk, Karl G. Linden, Megan E. J. Lott, Lewis J. Radonovich Jr., Bobby G. Warren, Richard D. Williamson, Richard L. Vincent, Sergio Gutiérrez‐Cortez, Carla Calderón Toledo, Joe Brown   +14 more
wiley   +1 more source

Clindamycin Induced Dysphagia – A Rare Concurrence

, 2013
Although dysphagia is a mechanical impedance in phase specific mechanism, drug induced dysphagia is an adverse event often caused due to esophagitis. Clindamycin is well known to cause esophagitis; itself causing dysphagia is not reported in literature ...
Nagamani, Banumathy; Post Graduate Institute of Medical Education and Research, Kumaran, Muthu Sendhil; Post Graduate Institute of Medical Education and Research (PGIMER), Panda, Naresh; Post Graduate Institute of Medical Education and Research (PGIMER), Sud, Parul; Post Graduate Institute of Medical Education and Research   +3 more
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