Results 191 to 200 of about 75,559 (213)
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Clindamycin-Associated Colitis
Annals of Internal Medicine, 1974Excerpt The subject of antibiotic-related, nonstaphylococcal pseudomembranous colitis has appeared sporadically in the medical literature for more than 20 years (1).
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Clindamycin and Colitis: A Review
Journal of Infectious Diseases, 1977Many studies have shown that clindamycin may cause pseudomembranous colitis, a potentially fatal complication. At present, prevention of this complication depends on (1) prescription of the drug only for specific severe infections, (2) early investigation and discontinuation of clindamycin if diarrhea ensues, and (3) vigorous supportive therapy.
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Clindamycin-Associated Colitis
JAMA: The Journal of the American Medical Association, 1973Although clindamycin hydrochloride hydrate is known to produce gastrointestinal symptoms, these have usually been reported as mild. We report three patients who had severe, protracted colitis associated with treatment with the drug.
Ralph F. Wells +2 more
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Clindamycin in malaria treatment
Journal of Antimicrobial Chemotherapy, 1990During the last decades intensive research has been undertaken to develop new drugs effective against resistant malaria. One line of research has been the screening of broad-spectrum antibiotics for their antiplasmodial properties.
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1972
Publisher Summary This chapter provides an overview of clindamycin, which is the generic name for 7(S)-chloro-7-deoxylincomycin. This compound is more active than lincomycin, but the bioassay procedures are essentially the same. The clindamycin blood assay is the same as the lincomycin assay.
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Publisher Summary This chapter provides an overview of clindamycin, which is the generic name for 7(S)-chloro-7-deoxylincomycin. This compound is more active than lincomycin, but the bioassay procedures are essentially the same. The clindamycin blood assay is the same as the lincomycin assay.
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Annals of Internal Medicine, 1975
Excerpt To the editor: The report of Tedesco, Barton, and Alpers (Ann Intern Med81:429-433, 1974) of an association of colitis with clindamycin use is lacking a placebo group as a necessary control...
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Excerpt To the editor: The report of Tedesco, Barton, and Alpers (Ann Intern Med81:429-433, 1974) of an association of colitis with clindamycin use is lacking a placebo group as a necessary control...
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Aqueous Stability of Clindamycin
Journal of Pharmaceutical Sciences, 1970The kinetics and mechanism of degradation of the antibiotic clindamycin were studied in buffered aqueous solution in the pH range 0.4-12. Clindamycin showed maximum stability at pH 3-5; however, high temperature studies indicated that not more than 10% degradation will occur in the pH range 1-6.5 after two years at 25°.
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JAMA: The Journal of the American Medical Association, 1976
To the Editor.— In the light of current appreciation of the risk of severe and sometimes lethal acute colitis due to clindamycin, I hope that most physicians will disagree with the conclusion of Christian and Krueger that "clindamycin appears to be a valuable additional drug in the treatment of acne." 1 With their 13-week treatment, noticeable ...
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To the Editor.— In the light of current appreciation of the risk of severe and sometimes lethal acute colitis due to clindamycin, I hope that most physicians will disagree with the conclusion of Christian and Krueger that "clindamycin appears to be a valuable additional drug in the treatment of acne." 1 With their 13-week treatment, noticeable ...
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