Sexual dimorphism of visceral pain has been documented in clinics and experimental animal models. Aside from hormones, emerging evidence suggests the sex-differential intrinsic neural regulation of pain generation and maintenance.
Namrata Tiwari, Liya Y. Qiao
doaj +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Selection of Optimal Adjuvant Chemotherapy Regimens for Early Breast Cancer and Adjuvant Targeted Therapy for HER2-Positive Breast Cancers: An American Society of Clinical Oncology Guideline Adaptation of the Cancer Care Ontario Clinical Practice Guideline Summary [PDF]
Neelima Denduluri +2 more
openalex +1 more source
Depression: An actionable outcome for those at clinical high-risk
J. Addington +15 more
openalex +1 more source
Mechanisms of parasite‐mediated disruption of brain vessels
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
A Model for Translating Ethnography and Theory into Culturally Constructed Clinical Practices
Bonnie K. Nastasi +7 more
openalex +2 more sources
MDS clinical diagnostic criteria for Parkinson's disease
R. Postuma +17 more
semanticscholar +1 more source
Time after time – circadian clocks through the lens of oscillator theory
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Editorial: Insights in neurotrauma: 2021
Mårten Risling
doaj +1 more source
NON-STANDARD KIDNEYS FOR TRANSPLANTS: CLINICAL MARGINS, MEDICAL MORALITY, AND THE LAW
Antonia Cronin, J. F. Douglas
openalex +2 more sources

