Results 171 to 180 of about 18,646,845 (356)

Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression

Molecular Oncology, EarlyView.
Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park, Jae Won Oh, Hyewon Chung, Jung Won Kwon, Yi Rang Na, Kwang Pyo Kim, Seung Hyeok Seok   +6 more
wiley   +1 more source

Generalizable Representation Learning for fMRI-based Neurological Disorder Identification [PDF]

arXiv
Despite the impressive advances achieved using deep learning for functional brain activity analysis, the heterogeneity of functional patterns and the scarcity of imaging data still pose challenges in tasks such as identifying neurological disorders. For functional Magnetic Resonance Imaging (fMRI), while data may be abundantly available from healthy ...
arxiv  

Clinical and Experimental Studies on Serum Angiotensinase Activity

, 1967
J Arai
openalex   +2 more sources

The generation of fibrinopeptide A in clinical blood samples: evidence for thrombin activity. [PDF]

, 1976
H. L. Nossel, Mary Ti, KL Kaplan, K. Spanondis, Tove Soland, V P Butler   +5 more
openalex   +1 more source

Definition of the Clinical Antibacterial Spectrum of Activity [PDF]

Clinical Microbiology and Infection, 1996
André Thabaut, C.J. Soussy, Fred Goldstein   +2 more
openaire   +3 more sources

Stochastic variation in the FOXM1 transcription program mediates replication stress tolerance

Molecular Oncology, EarlyView.
Cellular heterogeneity is a major cause of drug resistance in cancer. Segeren et al. used single‐cell transcriptomics to investigate gene expression events that correlate with sensitivity to the DNA‐damaging drugs gemcitabine and prexasertib. They show that dampened expression of transcription factor FOXM1 and its target genes protected cells against ...
Hendrika A. Segeren, Kathryn A. Wierenga, Frank M. Riemers, Elsbeth A. van Liere, Bart Westendorp   +4 more
wiley   +1 more source

Neuraminidase activities of clinical isolates of Diplococcus pneumoniae

, 1967
Richard T. Kelly, Sawyer Farmer, Donald Greiff   +2 more
openalex   +1 more source

Targeting PRAME directly or via EZH2 inhibition overcomes retinoid resistance and represents a novel therapy for keratinocyte carcinoma

Molecular Oncology, EarlyView.
The study evaluated the function and therapeutic implications of PRAME in basal cell carcinoma (BCC) and squamous cell carcinoma (SCC). The findings demonstrate that PRAME impairs keratinocyte differentiation pathways. Furthermore, PRAME impairs anticancer response to retinoid compounds in BCC and SCC cells.
Brandon Ramchatesingh, Amelia Martinez Villarreal, Philippe Lefrançois, Jennifer Gantchev, Sriraam Sivachandran, Samy Abou Setah, Ivan V. Litvinov   +6 more
wiley   +1 more source

Entrustable professional activities for bedside clinical teachers

BMC Medical Education
Background Bedside teaching is an important modality for training medical students and postgraduate trainees in clinical settings. Despite its significance, the effective practice of Bedside teaching has been declining over the past few decades.
Ayesha Rafiq, Ahsan Sethi
doaj   +1 more source

A Self-Supervised Model for Multi-modal Stroke Risk Prediction [PDF]

arXiv
Predicting stroke risk is a complex challenge that can be enhanced by integrating diverse clinically available data modalities. This study introduces a self-supervised multimodal framework that combines 3D brain imaging, clinical data, and image-derived features to improve stroke risk prediction prior to onset.
arxiv