Results 231 to 240 of about 18,646,845 (356)

In vitro comparative antimicrobial activity of cefpimizole against clinical isolates from five medical centers [PDF]

, 1985
Ronald N. Jones, Leona W. Ayers, T L Gavan, E. Gerlach, Herbert M. Sommers   +4 more
openalex   +1 more source

Clinical Appraisal of the Activity Index as a Measure of Rheumatoid Activity [PDF]

Arthritis & Rheumatism, 1968
openaire   +3 more sources

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

Molecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani, Gilgi Friedlander, Gili Perry, Nora Balint‐Lahat, Shlomit Gilad, Dana Morzaev‐Sulzbach, Anjana Shenoy, Noa Bossel Ben‐Moshe, Anya Pavlovsky, Rinat Bernstein‐Molho, Eytan Domany, Iris Barshack, Tamar Geiger, Bella Kaufman, Einav Nili Gal‐Yam   +14 more
wiley   +1 more source

Clinical significance of serum guanase activities determined by ammonia method using 8-azaguanine as substrate

, 1975
Susumu Ito, T Takaoka, Seiichiro Kishi, Hiromichi Okuda, Setsuro Fujii   +4 more
openalex   +2 more sources

MIF as an oncogenic driver of low‐heterogeneity melanomas

Molecular Oncology, EarlyView.
Shvefel and colleagues identified tumor‐secreted macrophage migration inhibitory factor (MIF) as an upregulated cytokine that mediates immune resistance in melanomas with low‐intratumoral heterogeneity. MIF and its functional paralogue D‐dopachrome tautomerase (D‐DT or MIF‐2) have overlapping but nonidentical signaling functions and are hypothesized to
Thuy T. Tran, Gabriela Athziri Sánchez‐Zuno, Rajan P. Kulkarni, Harriet M. Kluger, Richard Bucala   +4 more
wiley   +1 more source

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

Molecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez, Pablo Juanes‐Velasco, Marina L. García‐Vaquero, Conrad Droste, Alicia Landeira‐Viñuela, Miguel Alcoceba, Helena Fidalgo‐Gómez, Sara Misiego‐Herrero, Almudena Navarro‐Bailón, Mónica Baile, José M. Bastida, Jose Manuel Sanchez‐Santos, Rafael Góngora, Julia Almeida, Marcos Gonzalez‐Diaz, Alberto Orfao, Javier De Las Rivas, Manuel Fuentes   +17 more
wiley   +1 more source

Lysosomal Enzymes and Dibutyryl 3', 5'-Adenosine Monophosphate Basic and Clinical Studies on Lysosomal Enzyme Activities in Glioma Tissues and Glial Cells

, 1975
Iekado Shibata, Katsuyuki Sato, Mikio Matsumoto, Nobuyoshi Takasu, Sadatsugu NAGASAWA, Yoshikatsu Seiki, Nobuo YOSHII, F Yamada, Sakae FUKUDA   +8 more
openalex   +2 more sources

Clinical Observation on the Expectorant Activity of Ambroxol [PDF]

, 1985
Gil Ja Shin, Nan Ho Kyung, Tae Hee Min
openalex   +1 more source

Ubiquitination of transcription factors in cancer: unveiling therapeutic potential

Molecular Oncology, EarlyView.
In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley   +1 more source

Plasma Renin Activity in Hypertensive and Non-hypertensive Patients and Its Clinical Significance

, 1971
Masateru Eto
openalex   +2 more sources