Results 181 to 190 of about 10,946,773 (345)

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

Clinically-Orientated Anatomy: Five exemplars to portray the concept

, 2018
It has become almost a truism that, as for many biomedical sciences courses, gross anatomy tuition for healthcare curricula (including medicine and dentistry) should be integrated with clinical components to improve vocational relevance.
McHanwell, S., De Caro, R., Macchi, V., Spinosa, J.P., Riederer, B.M., Moxham, B., Porzionato, A.   +6 more
core  

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen, Jiancheng Cheng, Ruili Hou, Xiaoyuan Zheng, Li Su, Maria Moksnes Bjaanæs, Anna Karlsson, Maria Planck, Johan Staaf, Åslaug Helland, Manel Esteller, David C. Christiani, Feng Chen, Xiaofei Cao, Ruyang Zhang   +14 more
wiley   +1 more source

A three-dimensional digital study on clinical anatomy of the acetabulum in elderly population aged 65-84 years in inner Mongolia, China. [PDF]

BMC Geriatr
Zhenyu W, Yihan H, Sheng G, Xingquan L, Haiyan W, Zhiqiang W, Jiaqi L, Zhixuan Z, Jiayu W, Chunhao L, Yao J, Zhi W, Leilei J, Yumo L, Xiaohe L, Kai Z.   +15 more
europepmc   +1 more source

Clinical anatomy of the inferior labial gland: a narrative review. [PDF]

Gland Surg, 2021
Shen D, Ono K, Do Q, Ohyama H, Nakamura K, Obata K, Ibaragi S, Watanabe K, Tubbs RS, Iwanaga J.   +9 more
europepmc   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source

Unveiling Guyon's Canal: Insights into Clinical Anatomy, Pathology, and Imaging. [PDF]

Diagnostics (Basel)
Saran S, Reddy PS, Shirodkar K, Shah AB, Agarwal A, Shah A, Iyengar KP, Botchu R.   +7 more
europepmc   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Annals of Clinical Anatomy

, 2023
seyed khosrow tayebati
core  

Clinical anatomy by regions. 31260

, 2012
Includes index.ix, 754 pages :Widely praised for its clear and consistent organization, abundant illustrations, and emphasis on clinical applications, "Clinical Anatomy by Regions" delivers the user-friendly features and expert perspectives that have ...
Snell, Richard S. 31256 author
core