Results 91 to 100 of about 11,652,301 (264)
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin +2 more
wiley +1 more source
Addendum clinical guideline screening and prioritisation criteria
, 2012 Clinical guideline prioritisation criteria are commonly utilised by various key international bodies and organisations in order to select clinical guidelines for development, appraisal or endorsement at national, regional and local level.
National Clinical Effectiveness Committee
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Clinical pharmacology of novel anticancer agents: bioanalysis - clinical pharmacokinetics - mass balance studies [PDF]
, 2016 Cancer is already among the leading causes of death worldwide and the number of new cases is expected to rise by about 70% over the next two decades. Even though the number of new cases will rise, the survival rates are also increasing due to earlier ...
Pharmacoepidemiology and Clinical Pharmacology +1 more
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FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Major Trauma Audit: NCEC National Clinical Audit No.1
, 2016 There are 26 receiving trauma hospitals in Ireland. Since 2003, a number of reports have identified the need for trauma audit as a critical aspect of an integrated trauma system, to access the care and outcomes of severely injured patients in Ireland ...
National Clinical Effectiveness Committee (NCEC) +1 more
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Clinical trial simulations in paediatric oncology: A feasibility study from the Innovative Therapies for Children with Cancer Consortium [PDF]
, 2017 INTRODUCTION: Paediatric dose-finding studies are challenging to perform due to ethical reasons, the limited number of available patients and restricted number of blood samples.
Schellens, Jan H M +12 more
core +3 more sources
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
National Clinical Effectiveness Committee annual report 2013
, 2014 The National Clinical Effectiveness Committee (NCEC) was established as part of the Patient Safety First Initiative in September 2010. The NCECs mission is to provide a framework for national endorsement of clinical guidelines and audit to optimise ...
National Clinical Effectiveness Committee
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Stop Smoking: National Clinical Guideline No. 28
, 2022 This National Clinical Guideline has been developed by the Stop Smoking Guideline Development Group (GDG), within the Tobacco Free Ireland Programme, Strategy & Research, Healthcare Strategy, Health Service Executive (HSE).
Department of Health (DoH) +1 more
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Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source