Results 131 to 140 of about 413,875 (287)

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

Molecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes, Mario Ortega Duran, Solon Karapanagiotis, Alistair Martin, Meiling Gao, Riccardo Masina, Ramona Woitek, James Tanner, Fleur Tippin, Justine Kane, Jonathan Lay, Anja Brouwer, Stephen‐John Sammut, Suet‐Feung Chin, Davina Gale, Dana W. Y. Tsui, Sarah‐Jane Dawson, Nitzan Rosenfeld, Maurizio Callari, Oscar M. Rueda, Carlos Caldas   +20 more
wiley   +1 more source

Can single cell RNA sequencing reshape the clinical biochemistry of hematology: New clusters of circulating blood cells. [PDF]

Clin Transl Med, 2021
Fang H, Zeng Y, Zhang L, Chen C, Powell CA, Wang X.   +5 more
europepmc   +1 more source

Biochemistry of Women: Methods for Clinical Investigation. A. S. Curry and J. V. Hewitt, Eds. CRC Press, Cleveland, Ohio 44128, 1974, 354 pp [PDF]

, 1975
Ruth D McNair
openalex   +1 more source

BIOCHEMISTRY AND CLINICAL MEDICINE [PDF]

BMJ, 1923
openaire   +3 more sources

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

Molecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser, Florian Krumbach, Eyleen Corrales, Geoffroy Andrieux, Christian Preisinger, Franziska Liss, Alexandra Golzmann, Melanie Boerries, Kerstin Becker, Ruth Knüchel, Stefan Garczyk, Bernhard Lüscher   +11 more
wiley   +1 more source

Clinical Biochemistry Laboratory Biosafety Guidance during COVID-19 Pandemic [PDF]

National Journal of Laboratory Medicine, 2021
Sanjiv Kumar Bansal, Naveen Kumar Singh, Aakriti Khemka, Varsha Suryan, Arpita Suri   +4 more
doaj   +1 more source

How to Pass Examinations: A Personal View on Good Technique in Clinical Biochemistry Examinations [PDF]

, 1976
Alan M. Bold
openalex   +1 more source

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

Molecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu, Dilara Demirci, Sude Eris, Bengisu Dayanc, Ece Cakiroglu, Merve Basol, Merve Uysal, Gulcin Cakan‐Akdogan, Fang Liu, Mehmet Ozturk, Gökhan Karakülah, Serif Senturk   +11 more
wiley   +1 more source

Molecular differences between young and mature stria vascularis from organotypic explants and transcriptomics

iScience
Summary: The stria vascularis (SV) is an essential component of the inner ear that regulates the ionic environment required for hearing. SV degeneration disrupts cochlear homeostasis, leading to irreversible hearing loss, yet a comprehensive ...
Matsya Ruppari Thulasiram, Ryosuke Yamamoto, Rafal T. Olszewski, Shoujun Gu, Robert J. Morell, Michael Hoa, Alain Dabdoub   +6 more
doaj  

Patients with suspected myocardial infarction: their test request patterns for clinical biochemistry in a British and a Canadian cardiac care unit. [PDF]

, 1986
A R Henderson, M.D. Gardner
openalex   +1 more source