Results 201 to 210 of about 9,840,923 (344)

Laboratory testing in the emergency department: an Italian Society of Clinical Biochemistry and Clinical Molecular Biology (SIBioC) and Academy of Emergency Medicine and Care (AcEMC) consensus report

Clinical Chemistry and Laboratory Medicine, 2017
G. Lippi, M. Panteghini, S. Bernardini, L. Bonfanti, P. Carraro, I. Casagranda, M. Cavazza, F. Ceriotti, M. Ciaccio, D. Coen, D. Giavarina, F. Giostra, C. Paolillo, M. Plebani, G. Ricci, G. Cervellin   +15 more
semanticscholar   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Analysis of performance of clinical biochemistry laboratory using Sigma metrics and Quality Goal Index. [PDF]

Pract Lab Med, 2021
Goel P, Malik G, Prasad S, Rani I, Manhas S, Goel K.   +5 more
europepmc   +1 more source

UTILITY OF ADVANCES IN BIOCHEMISTRY IN CLINICAL REALITY OF DIABETES MELLITUS

, 2003
Nischit Baral, D Puri
openalex   +1 more source

National Academy of Clinical Biochemistry Laboratory Medicine Practice Guidelines: Use of Cardiac Troponin and B-Type Natriuretic Peptide or N-Terminal proB-Type Natriuretic Peptide for Etiologies Other than Acute Coronary Syndromes and Heart Failure [PDF]

, 2007
Alan H.B. Wu, A S Jaffe, Fred S. Apple, Robert L. Jesse, Gary L. Francis, David A. Morrow, L. Kristin Newby, Jan Ravkilde, W.H. Wilson Tang, Robert H. Christenson, Robert H. Christenson, Fred S. Apple, Christopher P. Cannon, Gary L. Francis, Robert L. Jesse, David A. Morrow, L. Kristin Newby, Jan Ravkilde, Alan B. Storrow, Wenyi Tang, Alan H.B. Wu, A. H.B. Wu   +21 more
openalex   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

The Role of Mediterranean Diet and Intermittent Fasting in Modulating Inflammation and Clinical Biochemistry Markers in Hereditary Cancer Syndromes: A Review. [PDF]

Curr Nutr Rep
Cacciabaudo F, Accardi G, Carta F, Tarantino S, Annunziata G, Russo TDB, Silva P, Candore G, Russo A, Ciaccio M.   +9 more
europepmc   +1 more source

Increased levels of two distinct elastase-like hydrolases in plasma during septicemia [PDF]

, 1983
Duswald, Karl-Heimo, Goldberg, David M., Jochum, Marianne, Nelles, L. P., Schnebli, H. P.   +4 more
core   +1 more source

Effectiveness of concept map in learning clinical aspects of biochemistry: A prospective interventional study from the Indian teaching hospital

Kumud Namdeorao Harley, Adarshlata Singh, Prerna Nandekar, Jayshri Sadashiv Jankar   +3 more
openalex   +2 more sources