Results 211 to 220 of about 9,840,923 (344)

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

Molecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui, Matthew A. Cottam, Muhammad Bilal Mirza, Keeli B. Lewis, Kristen K. Ciombor, Mary Kay Washington, Kamran Idrees   +6 more
wiley   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Hematology, Clinical Biochemistry, and Blood Cell Morphology Features of Captive Bothrops jararaca From Southeast Brazil. [PDF]

Vet Clin Pathol
Alcantara AO, Reis BMM, Fonseca JG, Sousa MAC, Roxo VHA, Souza GJ, Castro FFA, Souza GN, Fernandes J, Lemos ERS, Souza AM.   +10 more
europepmc   +1 more source

Assessing the influence of true hemolysis occurring in patient samples on emergency clinical biochemistry tests results using the VITROS^® 5600 Integrated system. [PDF]

Biomed Rep, 2021
Liu S, Li J, Ning L, Wu D, Wei D.
europepmc   +1 more source

Fluid heating system (SAF®): effects on clinical and biochemistry parameters in dogs submitted to inhalatory anesthesia [PDF]

, 2009
Ingrid Bueno Atayde, Leandro Guimarães Franco, Marco Augusto Machado Silva, Lorena Karine Soares, João Bosco Bittencourt, Maria Clorínda Soares Fíoravantí, Alinne Cardoso Borges, Luiz Antônio Franco da Silva   +7 more
openalex   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

Case-Based Learning in Clinical Biochemistry: Performance and Perception of MBBS Phase-I Students in Chhindwara Institute of Medical Sciences, Chhindwara, Madhya Pradesh, India. [PDF]

Cureus
Raghuwanshi K, Nagwanshi J, Kumar Jain B, Manore S, Petkar S, Gandhe M.   +5 more
europepmc   +1 more source

Clinical Biochemistry Impact of Glycated Albumin as a Potential Biomarker in Diabetes

, 2021
Hossam B Bahnasy
openalex   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Hematology and clinical biochemistry reference intervals for companion pigs using the ADVIA 2120 and Cobas c501. [PDF]

PeerJ
Schaefer DMW, Videla R, Smith JS, Mulon PY, Flatland B, Zhu X.   +5 more
europepmc   +1 more source