Results 51 to 60 of about 9,840,923 (344)

Dynamics of biochemical parameters in lambs during the first four months of life

open access: yesRevista Brasileira de Zootecnia, 2020
We aimed to verify whether age influences the biochemical profile of healthy lambs during the first four months of life by characterizing the dynamics of its parameters and verifying whether there are differences between the profiles of growing animals ...
Damaris Ferreira de Souza   +7 more
doaj   +1 more source

Activity-based protein profiling of human and plasmodium serine hydrolases and interrogation of potential antimalarial targets

open access: yesiScience, 2022
Summary: Malaria remains a global health issue requiring the identification of novel therapeutic targets to combat drug resistance. Metabolic serine hydrolases are druggable enzymes playing essential roles in lipid metabolism. However, very few have been
Dara Davison   +3 more
doaj   +1 more source

An approach for estimating measurement uncertainty in medical laboratories using data from long-term quality control and external quality assessment schemes [PDF]

open access: yes, 2017
The present study was prompted by the ISO 15189 requirements that medical laboratories should estimate measurement uncertainty (MU)
Aita, Ada   +4 more
core   +1 more source

Isocitrate Dehydrogenase Mutations in Glioma: Genetics, Biochemistry, and Clinical Indications

open access: yesBiomedicines, 2020
Mutations in isocitrate dehydrogenase (IDH) are commonly observed in lower-grade glioma and secondary glioblastomas. IDH mutants confer a neomorphic enzyme activity that converts α-ketoglutarate to an oncometabolite D-2-hydroxyglutarate, which impacts ...
Yang Liu   +4 more
semanticscholar   +1 more source

Pengaruh Ekstrak Etanol (Penorema Canescens Jack) terhadap Apoptosis Sel Hela

open access: yesMajalah Kedokteran Andalas, 2023
Tujuan: untuk mengetahui pengaruh ekstrak etanol daun sungkai dengan konsentrasi IC25 (34,24 μg/ml), IC50 (55,08 μg/ml), dan IC75 (88,51 μg/ml) terhadap apoptosis sel HeLa.
Rizka Farahiya
doaj   +1 more source

Diagnosis and treatment of canine hypoadrenocorticism [PDF]

open access: yes, 2018
Canine hypoadrenocorticism (Addison’s disease), the ‘great pretender’ of internal medicine, is a disease that should be frequently considered as a differential diagnosis of several clinical presentations, albeit it is less commonly the actual cause of ...
Gunn, Eilidh   +2 more
core   +1 more source

Campus Update: April 1994 v. 6, no. 3 [PDF]

open access: yes, 1994
Monthly newsletter of the BU Medical ...
Boston University Medical Center
core   +4 more sources

A novel human glucocorticoid receptor SNP results in increased transactivation potential. [PDF]

open access: yes, 2017
Glucocorticoids are one of the most widely used therapeutics in the treatment of a variety of inflammatory disorders. However, it is known that there are variable patient responses to glucocorticoid treatment; there are responders and non-responders, or ...
Cho, Kiho   +5 more
core   +3 more sources

Pathogenic Germline PALB2 and RAD50 Variants in Patients With Relapsed Ewing Sarcoma

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Approximately 10% of patients with Ewing sarcoma (EwS) have pathogenic germline variants. Here, we report two cases: first, a novel germline pathogenic variant in partner and localizer of BRCA2 (PALB2) in a patient with a late EwS relapse. Its impact on homologous recombination is demonstrated, and breast cancer risk is discussed.
Molly Mack   +12 more
wiley   +1 more source

Clinical Characteristics and Prognostic Risk Factors for Pediatric B‐Cell Lymphoblastic Lymphoma: A Multicenter Retrospective Cohort Study for China Net Childhood Lymphoma

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background B‐cell lymphoblastic lymphoma (B‐LBL) represents a rare variety of non‐Hodgkin lymphoma, with limited research on its biology, progression, and management. Methods A retrospective analysis was performed on the clinical characteristics of 256 patients aged ≤18 years who received treatment under the China Net Childhood Lymphoma (CNCL)‐
Zhijuan Liu   +20 more
wiley   +1 more source

Home - About - Disclaimer - Privacy