Predictors of <i>Candida auris</i> Infection in Previously Colonized Patients: A Retrospective Cohort Study from a Large Tertiary Reference Center. [PDF]
Ergün N +4 more
europepmc +1 more source
Gamma Knife treatment planning using knowledge‐based reinforcement learning
Abstract Background Inverse planning is often used for Gamma Knife radiosurgery, allowing clinicians to mathematically specify desired clinical objectives and dose limits. The objectives are controlled by weights that are manually tuned to find the desired trade‐off, which varies from case to case.
Christopher Huynh +5 more
wiley +1 more source
Long-Read HiFi Genome Sequencing Resolves Retrotransposon-Mediated Deletions in TANGO2 Deficiency Disorder. [PDF]
Sabbagh Q +8 more
europepmc +1 more source
ABSTRACT Optimal cephalexin and cefadroxil dosing for skin and soft tissue infections (SSTIs) is unclear. We summarize clinical and pharmacokinetic/pharmacodynamic (PK/PD) data that compare dosing strategies for SSTIs. Additionally, we conduct population PK target attainment simulations for varying doses of cephalexin and cefadroxil for Staphylococcus ...
Jonathan H. Ryder +6 more
wiley +1 more source
Case Report: Deciphering a <i>de novo</i> complex chromosomal rearrangement causing premature ovarian insufficiency, short stature, and mild intellectual disability using long-read sequencing. [PDF]
Cheng Q +6 more
europepmc +1 more source
A total of 110 Staphylococcus aureus isolates from cattle were analysed to determine the epidemiological cut‐off value (ECOFF) for cefquinome. Minimum inhibitory concentrations (MICs) were determined using standardised agar dilution and broth microdilution methods following 24 h incubation.
Ijaz Ahmad +8 more
wiley +1 more source
Preclinical models for evaluating psychedelics in the treatment of major depressive disorder
Psychedelic drugs have seen a resurgence in interest as a next generation of psychiatric medicines with potential as rapid‐acting antidepressants (RAADs). Despite promising early clinical trials, the mechanisms which underlie the effects of psychedelics are poorly understood.
Laith Alexander +5 more
wiley +1 more source
Diagnostic Performance of Combination Disk and CIM Tests for Carbapenemase Detection in Enterobacterales Compared with Real-Time Multiplex PCR. [PDF]
Çabuk A +4 more
europepmc +1 more source
Advances in genomic, proteomic, and transcriptomic technologies are transforming the diagnosis of genetic myopathies. When integrated with traditional muscle pathology, multi‐omics approaches improve diagnostic yield, clarify disease mechanisms, and support more precise, mechanism‐based therapeutic strategies for patients with neuromuscular disorders ...
Ludmila Alem +2 more
wiley +1 more source
Prevalence of substance use during pregnancy in New Jersey: Investigating the effects of the COVID-19 public health emergency. [PDF]
Gulchin A +4 more
europepmc +1 more source

