Results 251 to 257 of about 68,369 (257)
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Different breakpoints interpretation yielded distinct resistance rates to moxifloxacin of clinically significant anaerobic bacteria

Anaerobe, 2021
The aim of this study was to describe the differences in antimicrobial susceptibility to moxifloxacin between European Committee on Antimicrobial Susceptibility Testing (EUCAST) and Clinical and Laboratory Standards Institute (CLSI) in anaerobic microorganisms.
Fernando Cobo   +2 more
openaire   +2 more sources

Strategy for Breakpoint Cluster Region Analysis in Chronic Myelocytic Leukemia in a Routine Clinical Laboratory

American Journal of Clinical Pathology, 1990
Despite the increasing reliance on breakpoint cluster region (bcr) determinations in diagnosis of chronic myelocytic leukemia (CML), few reports have dealt with the practical aspects of specimen analysis. In the setting of a routine molecular diagnostics laboratory, samples from 68 patients with active CML were evaluated for bcr rearrangements, with ...
Haber, L. M.   +7 more
openaire   +3 more sources

Investigation of the clinical breakpoints of piperacillin–tazobactam against infections caused by Pseudomonas aeruginosa

Journal of Infection and Chemotherapy, 2012
The pharmacokinetics-pharmacodynamics (PK-PD) breakpoint of piperacillin/tazobactam (PIPC/TAZ) for hospital-acquired pneumonia (HAP) and Pseudomonas aeruginosa-induced bacteremia is controversial, since the susceptibility of P. aeruginosa to PIPC/TAZ is known to be lower than that set by the Clinical Laboratory Standards Institute (CLSI), ≤64 mg/L. The
Yuka, Yamagishi   +5 more
openaire   +2 more sources

Who defines resistance? the clinical and economic impact of antimicrobial susceptibility testing breakpoints

Seminars in Pediatric Infectious Diseases, 2004
Antimicrobial susceptibility test breakpoints are necessary for the correct clinical interpretation of quantitative or qualitative susceptibility test values of antibacterial agents. Breakpoints are selected by regulatory bodies or professional groups (eg, the National Committee for Clinical Laboratory Standards) based on an extensive review of the ...
openaire   +2 more sources

On the Xq13 Breakpoint: Clinical and Cytogenetic Observations in a Patient with Acute Myelogenous Leukemia

Acta Haematologica, 1983
Cytogenetic study in a case of acute myelogenous leukemia revealed the presence of two identical dicentric marker chromosomes derived from an X with Xq13 breakpoints. Clinical and cytochemical findings suggest that the patient was affected by idiopathic acquired sideroblastic anemia before the acute leukemia.
SESSAREGO, MARIO   +3 more
openaire   +3 more sources

Clinical impact of breakpoint position within M-bcr in chronic myeloid leukemia.

Leukemia, 1993
We have analyzed the M-bcr breakpoint position in 133 Philadelphia-positive chronic myeloid leukemia patients and correlated the findings with clinical, hematologic, and cytogenetic data. We also investigated the splicing pattern of the BCR-ABL mRNA in 30 patients, using reverse transcriptase PCR.
T, Fioretos   +8 more
openaire   +1 more source

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