Cognitive behavioral therapy with and without biofeedback in fibromyalgia: Assessment of functional and clinical change. [PDF]
Health Psychol Open, 2022 Govillard L, Gorbeña S, Iraurgi I.
europepmc +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Wellcome Open ResearchBackground Human behaviours have been classified in domains such as health, occupation and sustainability. We aimed to develop a broadly applicable behavioural framework to facilitate integrating evidence across domains.
Alison J. Wright +12 more
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Role of the Advanced Practitioner in Leading Change in Primary Care.
International Journal of Endorsing Health Science Research, 2023 The role and recognition of advanced clinical practitioners (ACPs) have been subject to debate in various healthcare settings. Therefore, this review aims to critically analyze the role of ACPs in leading change within primary care services.
Qaiser Shahzad Chishty +1 more
doaj
How clinical teaching teams deal with educational change: ‘we just do it’
BMC Medical Education, 2019 Background In postgraduate medical education, program directors are in the lead of educational change within clinical teaching teams. As change is part of a social process, it is important to not only focus on the program director but take their other ...
L. Bank +5 more
doaj +1 more source
Assessing Clinical Change in Individuals Exposed to Repetitive Head Impacts: The Repetitive Head Impact Composite Index. [PDF]
Front Neurol, 2021 Bernick C +4 more
europepmc +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Synthesis and Evaluation of Some New Aza-B-homocholestane Derivatives as Anticancer Agents
Marine Drugs, 2014 Using analogues of some marine steroidal oximes as precursors, a series of aza-B-homocholestane derivatives possessing different substituted groups at the 3-position of the steroidal nucleus were synthesized.
Yanmin Huang +7 more
doaj +1 more source
Evidence, not eminence, for surgical management during COVID-19: a multifaceted systematic review and a model for rapid clinical change. [PDF]
BJS Open, 2021 Kovoor JG +4 more
europepmc +1 more source