Results 101 to 110 of about 1,299,269 (307)

Preparation for the Implementation of the International Classification of Diseases 11th Revision: A Survey on Clinical Coders' Knowledge of the International Classification of Diseases 11th Revision, Educational Needs, and Readiness to Accept New Roles: A Cross‐Sectional Study

Health Science Reports
Background and Aims Studies have shown that the knowledge and skills of clinical coders impact the quality of clinical coding, and professional training for clinical coders is essential to ensure coding quality.
Javad Zarei, AliMohammad Hadianfard, Abbas Sheikhtaheri   +2 more
doaj   +1 more source

Whole genome sequencing for mutation discovery in a single case of lysosomal storage disease (MPS type 1) in the dog. [PDF]

, 2020
Mucopolysaccharidosis (MPS) is a metabolic storage disorder caused by the deficiency of any lysosomal enzyme required for the breakdown of glycosaminoglycans.
Aguilar, Miriam, Ancona, Devin, Bannasch, Danika, Brown, C. Titus, Cowan, Tina, Knipe, Marguerite, Mansour, Tamer, Moore, Bret, Seada, Haitham, Sebbag, Lionel, Sebbag, Lionel, Thomasy, Sara, Vernau, Karen, Woolard, Kevin   +13 more
core   +3 more sources

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Beyond Volume: The Impact of Complex Healthcare Data on the Machine Learning Pipeline

, 2017
From medical charts to national census, healthcare has traditionally operated under a paper-based paradigm. However, the past decade has marked a long and arduous transformation bringing healthcare into the digital age.
A Arcuri, AL Rector, AM Wood, AS Glas, B Kulis, C Cortes, C Sammut, CC Diamond, CD Kidd, CR MacIntyre, DP Lewis, E Koumoundouros, E Rahm, EM Knorr, ES Fisher, GE Box, GM Weber, H Carter, H He, H Meyer, H Quan, HH Hoos, I Yoo, J Andreu-Perez, J Fan, J Zhao, JD Lafferty, JM Bland, JW Graham, K Lange, KP Murphy, LA King, LM Collins, M Azarm-Daigle, M Kantardzic, M Sokolova, MA Stoto, N Oreskes, PB Jensen, PK Lindenauer, PM Visscher, RJ Little, V López, V Sessions, VN Vapnik, W Raghupathi, Y Luo   +46 more
core   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Cost- effectiveness of HPV vaccination regime: comparing twice versus thrice vaccinations dose regime among adolescent girls in Malaysia

BMC Public Health, 2016
Background The HPV vaccine was introduced to Malaysian national immunization programme in 2010. The current implementation age of HPV vaccination in Malaysian is at the age of 13 years school girls, given according to a 3 doses protocol which may ...
Syed Aljunid, Nimetcan Mehmet Orhun, Amrizal M Nur, Mohd Rushdan Md Noor, Sharifa Ezat Wan Puteh   +4 more
doaj   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Enhancing Clinical Coding Expertise in Indonesia’s National Health Insurance Program

Jurnal Jaminan Kesehatan Nasional
Coding medical records using classification systems can cause inconsistencies, sometimes leading to claim disputes. In January 2021, 440,749 disputed cases were reported, with a total disputed cost amounting to Rp873,111,325,287 for referral healthcare ...
Novianti Br. Gultom, Arisandy Saputra, Dwi Surini, Erwinsyah, Elsa Novelia, Johana, Vernanda Dosiema, Intan Corina, Miranti Ratnafuri, Fallah Adi Wijayanti, Dedy Setyawan, Egar Januar Prakarsa, Sarman Pali'padang, Gilang Yoga Wardanu, Lia Yulianti Surosa, Jack Langenbrunner, John Blake   +16 more
doaj   +1 more source

Manual annotation of narrative patient charts – Finnish experiences related to a multilingual text corpus

Finnish Journal of eHealth and eWelfare, 2019
ASSESS CT project evaluated SNOMED CT use for patient information exchange in EU. Finland was one of the six participating EU states. The Finnish part of the research was conducted in the National Institute for Health and Welfare. The Finnish experiences
Päivi Mäkelä-Bengs, Päivi Hämäläinen, Virpi Kalliokuusi, Riikka Vuokko   +3 more
doaj   +1 more source