Results 131 to 140 of about 201,869 (314)

Potent Cross‐neutralizing Antibodies Reveal Vulnerabilities of Henipavirus Fusion Glycoprotein

open access: yesAdvanced Science, EarlyView.
Hendra and Nipah viruses (HNVs) pose significant threats to global health. This work reports potent cross‐neutralizing antibodies targeting the fusion glycoprotein (F) and reveals shared features of these antibodies and vulnerabilities of F, thereby guiding the rational design of countermeasures against HNVs and similar pathogens.
Yi Ren   +19 more
wiley   +1 more source

Conceptualising quality early childhood education: Learning from young children in Brazil and South Africa through creative and play‐based methods

open access: yesBritish Educational Research Journal, EarlyView., 2023
Abstract Early childhood has increasingly been acknowledged as a vital time for all children. Inclusive and quality education is part of the United Nations Sustainable Development Goals, with the further specification that all children have access to quality pre‐primary education.
Laura H. V. Wright   +8 more
wiley   +1 more source

American College of Cardiology/American Heart Association Clinical Competence Statement on Invasive Electrophysiology Studies, Catheter Ablation, and Cardioversion [PDF]

open access: bronze, 2000
Cynthia M. Tracy   +12 more
openalex   +1 more source

A Smart Single‐Loop‐Mediated Isothermal Amplification Facilitates Flexible SNP Probe Design for On‐Site Rapid Differentiation of SARS‐CoV‐2 Omicron Variants

open access: yesAdvanced Science, EarlyView.
The ssLAMP method amplifies the nucleic acid of pathogen and identifies SNP mutations. By combining the portable detection device with smartphone‐based analysis software, enables rapid, on‐site SNP detection and genotyping of SARS‐Cov‐2 Omicron variants, providing a cost‐effective and field‐deployable solution for precise pathogen identification in ...
Qijie Lin   +19 more
wiley   +1 more source

Electrochemical‐Genetic Programming of Protein‐Based Magnetic Soft Robots for Active Drug Delivery

open access: yesAdvanced Science, EarlyView.
This manuscript presents a protein‐based soft robot for active drug delivery. Stimuli‐responsive protein is rationally designed and processed into the substrate of robots. Superparamagnetic Fe3O4 nanoparticles are patterned on the substrate using an electrochemical method, enabling the robot to respond to external physical fields.
Hang Zhao   +12 more
wiley   +1 more source

Institutional learning curve and factors of prolonged operation time of robotic distal pancreatectomy: An analysis of an initial 117 cases

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
This study verified the effective implementation of robotic distal pancreatectomy as the standard approach in our strategic robotic surgical oncology program. Although an institutional learning curve was observed, the robotic surgery program successfully expanded the number of primary operating surgeons while maintaining stable short‐term outcomes ...
Yuki Hirata   +9 more
wiley   +1 more source

Designed Biomaterial‐Enhanced Cell Transplantation for Neural Tissue Engineering

open access: yesAggregate, EarlyView.
Biomaterials offer a promising solution for cell transplantation in the central nervous system by creating a protective environment that enhances cell survival, integration, and functional recovery in preclinical models of neurological disorders. ABSTRACT Cell transplantation therapy in the central nervous system is hindered by limited survival and ...
Yun Tang   +3 more
wiley   +1 more source

Macrocyclic Peptide Probes for Immunomodulatory Protein CD59: Potent Modulators of Bacterial Toxin Activity and Antibody‐Dependent Cytotoxicity

open access: yesAngewandte Chemie, EarlyView.
This study presents novel macrocyclic peptides with low nanomolar affinity for CD59, an immunomodulatory cell surface receptor associated with human disease. Crystallographic and structure‐activity relationship (SAR) studies reveal peptide CP‐06 mimics the binding of biologically relevant CD59 interaction partners. Dimeric and lipidated CP‐06 analogues
Jasmine K. Bickel   +12 more
wiley   +2 more sources

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