Artificial Intelligence Literacy, Critical Thinking Disposition, and Clinical Competence Among Nursing Students: A Cross-Sectional Study. [PDF]
Jeong Y, Kim N, Park S, Seok J.
europepmc +1 more source
Programmable Nanobody‐Targeting Chimeras Enable Intracellular Viral Protein Degradation
Nab‐TAC enables targeted degradation of HBV surface antigen (HBsAg) in vivo. By fusing nanobody‐based recognition domains with programmable proteasome‐recruiting degradation signals, Nab‐TAC reduces HBsAg levels in a hydrodynamic HBV mouse model. ABSTRACT Chronic hepatitis B virus (HBV) infection remains a major global health challenge, largely because
Max Yu‐Chen Pan +11 more
wiley +1 more source
Barriers and enablers in implementing strategies to maintain clinical competence of midwife educators: a scoping review. [PDF]
Ferguson A +4 more
europepmc +1 more source
Competence in Health Care - An Industrial Systems Analysis Using Competence Bloc Theory to Compare European and US Health Care [PDF]
While European health care systems are mostly public and similar the contrast is large to the US health industry based to a large extent in the market. Using competence bloc theory the industrial potential of Swedish and European health care is assessed ...
Eliasson, Gunnar, Eliasson, Åsa
core
Cancer‐Associated BCL‐2 Mutants Reveal Mechanisms Towards Venetoclax Resistance
Venetoclax (VEN) resistance in chronic lymphocytic leukemia arises from diverse BCL2 mutations. We map mechanisms contributing to VEN resistance across common BCL‐2 variants. G101V and D103Y reduce drug binding and increase sequestration of pro‐apoptotic proteins. V156D blocks VEN allosterically.
Jonas Aufdermauer +9 more
wiley +1 more source
Emotional intelligence and clinical competence among nursing interns: a structural equation modeling study. [PDF]
Alshutwi SS, Aldhafeeri NA, Alenezi L.
europepmc +1 more source
NSD2 coordinates the neurogenic‐to‐gliogenic transition in the developing neocortex through H3K36me2‐dependent activation of EGFR–ERK signaling. Loss of NSD2 disrupts astroglial and oligodendroglial development, whereas ERK activation rescues gliogenic defects in vitro and in vivo.
Hanxue Chen +7 more
wiley +1 more source
Balancing Theoretical Knowledge and Clinical Competence: Digital Distractions and Exam-centric Medical Education in India. [PDF]
Nair AR.
europepmc +1 more source
In PWS‐ASPCs, FOSL1 drives the expression of SPSB1. SPSB1, as part of the ESC complex, further binds to HDAC1 and promotes K29‐linked and K48‐linked polyubiquitination of HDAC1. These modifications facilitate the degradation of HDAC1 through the ALP and UPS pathways, respectively.
Hongrui Chen +5 more
wiley +1 more source

