Results 141 to 150 of about 201,869 (314)

Engineering Bodipy‐Based Metal–Organic Frameworks for Efficient Full‐Spectrum Photocatalysis in Amide Synthesis

open access: yesAngewandte Chemie, EarlyView.
Three highly stable bodipy‐based metal–organic frameworks (BMOFs) were synthesized by treating dicarboxyl‐functionalized bodipy ligands with Zr‐oxo clusters. Featuring the distinct bodipy scaffold in the framework, these BMOFs displayed high reactivity in heterogenous photocatalytic C─H bond activation of N,N‐dimethylanilines to access amides under ...
Binhui Liu   +9 more
wiley   +2 more sources

ExplORRNet: An interactive web tool to explore stage-wise miRNA expression profiles and their interactions with mRNA and lncRNA in human breast and gynecological cancers

open access: yesNon-coding RNA Research
Background: MicroRNAs (miRNAs) are key regulators of gene expression that have been implicated in gynecological and breast cancers. Understanding the cancer stage-wise expression patterns of miRNAs and their interactions with other RNA molecules in ...
Ankita Lawarde   +6 more
doaj  

Promoting AI Competencies for Medical Students: A Scoping Review on Frameworks, Programs, and Tools [PDF]

open access: yesarXiv
As more clinical workflows continue to be augmented by artificial intelligence (AI), AI literacy among physicians will become a critical requirement for ensuring safe and ethical AI-enabled patient care. Despite the evolving importance of AI in healthcare, the extent to which it has been adopted into traditional and often-overloaded medical curricula ...
arxiv  

American College of Cardiology/American Heart Association Clinical Competence Statement on Echocardiography [PDF]

open access: bronze, 2003
Miguel A. Quiñones   +20 more
openalex   +1 more source

A Hypoxia‐Triggered Bioreduction of Hydrophilic Type I Photosensitizer for Switchable In Vivo Photoacoustic Imaging and High‐Specificity Cancer Phototherapy

open access: yesAngewandte Chemie, EarlyView.
A hydrophilic type I phototherapeutic agent (NanoPcN8O) was developed which selectively responded to hypoxic tumor microenvironments and switched on type I photodynamic and photothermal effects as well as a photoacoustic signal for activatable photoacoustic imaging and tumor phototherapy.
Yuan‐Yuan Zhao   +6 more
wiley   +2 more sources

Simulation-based Bayesian predictive probability of success for interim monitoring of clinical trials with competing event data: two case studies [PDF]

open access: yesarXiv
Bayesian predictive probabilities of success (PPoS) use interim trial data to calculate the probability of trial success. These quantities can be used to optimize trial size or to stop for futility. In this paper, we describe a simulation-based approach to compute the PPoS for clinical trials with competing event data, for which no specific methodology
arxiv  

Functional Characterization of a Genetic Variant in the 5′ UTR of APC 1B Promoter in a Familial Adenomatous Polyposis Family

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Pathogenic germline variants in the APC gene result in familial adenomatous polyposis (FAP) which can escalate into colon cancer. Standard clinical testing failed to identify pathogenic variants in a 4‐generation FAP family. We identified and assessed co‐segregation of a 5′ untranslated region (UTR) variant, NM_001127511.3 (APC) c.‐40G>A ...
Brendon Young   +9 more
wiley   +1 more source

Mental health literacy among primary healthcare workers in South Africa and Zambia

open access: yesBrain and Behavior, Volume 12, Issue 12, December 2022., 2022
Graphical Abstract Abstract Background In developing countries, mental health literacy (MHL) still needs to be improved due to the high prevalence of mental disorders. It is widely recognized that MHL can improve health outcomes for both individuals and populations.
Joonas Korhonen   +11 more
wiley   +1 more source

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