Results 161 to 170 of about 6,428,705 (303)

Targeting β2‐Adrenergic Receptor Stability With Lycorine Reveals a Host‐Directed Pathway for Antiviral Defense Against Poxviruses

Advanced Science, EarlyView.
Chronic stress drives autophagy‐mediated β2‐AR degradation, impairing antiviral immunity and promoting poxvirus lethality. Lycorine directly stabilizes β2‐AR to restore host defense, suppress excessive inflammation and improve survival. ABSTRACT Psychological stress is a pervasive yet poorly understood modulator of infectious disease outcomes. Here, we
Xin Zhang, Shuqin Xu, Zixuan Zhang, Chenwen Wan, Xiaoqin Wang, Peihua Wang, Huini Yang, Tianxiao Huang, Yijia Yuan, Faiza Atique, Rui Yang, Yingli He, Zhijun Liu   +12 more
wiley   +1 more source

Objective Structured Clinical Examination for competence assessment

, 2015
The Objective Structured Clinical Examination (OSCE) is designed to assess clinical competence and is primarily used to assess basic clinical skills. It is a versatile assessment tool to evaluate dental students in a clinical setting. Dental students are
Chu, CH
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From Compassionate Intuition to Clinical Competence: Spiritual Care Among Palliative Care Professionals in Ecuador. [PDF]

Healthcare (Basel)
Bonilla-Sierra P, Pérez-Jiménez JM, De Diego-Cordero R.   +2 more
europepmc   +1 more source

NICE: A Two‐Step Non‐Invasive Framework for Embryo cfDNA Read Enrichment and Quality Assessment

Advanced Science, EarlyView.
The non‐invasive NICE framework, built on an ensemble stacking machine learning model, prioritizes embryos by analyzing cell‐free DNA from spent culture medium. By integrating multimodal signals, including genomic and epigenetic profiles, this automated approach standardizes morphological assessment without human bias, paving the way for more precise ...
Xueya Zhou, Shu Ding, Zhenyi Zhang, Qiaoling Shangguan, Jie Qiao, Peijie Zhou, Yidong Chen   +6 more
wiley   +1 more source

Clinical oral examinations: Assessment of competence in radiation therapy

, 2009
Matching assessment strategies to learning outcomes in radiation therapy education is of the utmost importance. Assessing clinical competence requires that ‘competence’ be clearly defined prior to the start of any clinical programme.
C Poole (7770833), M Leech (3999329), A Craig (13459938), S Ni Chuinneagain (20885138), M Coffey (20193966), M Broderick (20885135), J Byrne (9032522)   +6 more
core  

Clinical Competence of Graduating Student Nurses in Higher Education Institutions. [PDF]

Acta Med Philipp
Aquino RMA, Antonio GCB, Boado JLE, Cruz AMI, Domingo SGS, Gamboa FGO, Laguatan JL, Manangan SES, Ordonio RGT, Quisias AA, Tamondong AR.   +10 more
europepmc   +1 more source

A Synthetic Platform for Antibody Junctional Diversification Beyond Natural Constraints

Advanced Science, EarlyView.
ARESEC is a synthetic platform that reconstructs functional V(D)J recombination in HEK293T cells. By introducing RSS elements and co‐expressing RAG1/2 and TdT across all three antibody CDRs, it enables programmable junctional diversification and direct generation of high‐affinity variants targeting PD‐1/PD‐L1, overcoming the evolutionary constraints of
Wang Liu, Jun Yang, Yuhang Zhang, Xiaoli Xue   +3 more
wiley   +1 more source

Food-drug interactions knowledge and clinical competence among registered dietitians. [PDF]

BMC Med Educ
Beirão S, Rossoni C, Ferreira-Pêgo C, Costa JG.   +3 more
europepmc   +1 more source

CHST1 Drives Immunotherapy Resistance in Triple‐Negative Breast Cancer by Orchestrating an Immunosuppressive Microenvironment via the NKRF–CCL20–Macrophage Axis

Advanced Science, EarlyView.
Proposed model of CHST1‐associated immune remodeling in triple‐negative breast cancer. In CHST1‐low tumors, greater nuclear accumulation of NKRF is associated with repression of an NF‐κB‐related CCL20 transcriptional program and an immune‐inflamed microenvironment.
Shu‐Hao Jiang, Xiao‐Han Ying, Ruo‐Qing Wang, Qun Zhang, Li Chen, Zhi‐Ming Shao, Jun‐Jie Li   +6 more
wiley   +1 more source

Relationship between Self-Efficacy and Clinical Skill Competence of Nursing Students

, 2006
Purpose: This study was done to identify the relationship between self-efficacy and clinical skill competence of nursing students. Method: The participants in the study were 375 student nurses enrolled in 3rd & 4th year of a BSN program in Seoul and ...
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