Results 171 to 180 of about 628,991 (311)

Nursing students' development of clinical competence through the use of reflection prompts based on the nursing process during clinical education: a qualitative longitudinal study. [PDF]

BMC Med Educ
Löfgren U, Wälivaara BM, Strömbäck U, Lindberg B.   +3 more
europepmc   +1 more source

Improved Systemic Immunochemotherapy Employing an Oxaliplatin‐TLR7/8 Agonist Prodrug Strategy

Advanced Science, EarlyView.
A platinum(IV) prodrug is developed to systemically deliver the TLR7/8 agonist gardiquimod. Tumor‐targeting is mediated by an albumin‐binding maleimide, which limits premature complex activation. Ox‐Gardi‐Mal accumulates specifically in the tumor, where it activates the immune system.
Michael Gutmann, Martijn Dijkstra, Philipp Salomon, Jamie Cowles, Anja Federa, Dina Baier, Carola Jaunecker, Iemima Semerean, Venla Karvonen, Christine Pirker, Maria Sibilia, Dietmar Herndler‐Brandstetter, Petra Heffeter, Bernhard K. Keppler, Christian R. Kowol, Walter Berger   +15 more
wiley   +1 more source

EVENS (Evaluation Nursing Students): A Mobile Application to Enhance Nursing Students' Clinical Competence and Self-Efficacy-A Quasi-Experimental Study. [PDF]

Nurs Rep
Guzmán-Almagro MI, Carro RM, Izaguirre-García P, Caballero-Díaz FF, Leñero-Cirujano M, Oter-Quintana C, González-Gil MT, Alcolea-Cosín MT, García-García C, Parro-Moreno AI.   +9 more
europepmc   +1 more source

De Novo Design and Directed Evolution Refinement of Mirror‐Image Protein Binders Targeting Interleukin‐4

Advanced Science, EarlyView.
This study presents the de novo design and directed evolution of a mirror‐image D‐protein inhibitor targeting human interleukin‐4 (IL‐4). The engineered molecule exhibits nanomolar binding affinity for IL‐4 and effectively inhibits IL‐4–mediated signaling.
Liqing Xu, Yuxiang Ren, Tongyue Wang, Hongyong Li, Yue Yao, Lei Liu, Ke Sun, Peilong Lu   +7 more
wiley   +1 more source

A workplace-based learning program on clerkship of internal medicine improves medical student's clinical competence: a retrospective comparative study. [PDF]

BMC Med Educ
Wang JN, Lv H, Sun Y, Cao W, Jiang L.
europepmc   +1 more source

Deciphering and Targeting the Schwannoma‐Neuron‐Macrophage Crosstalk for the Treatment of Schwannomatosis and Associated Pain

Advanced Science, EarlyView.
We established patient‐derived SWN cell lines and orthotopic PDX models that recapitulate patient pain phenotypes, alongside a novel intravital DRG imaging platform to track macrophage infiltration and neuronal pain responses. Using these models, we define HMGB1–CCL2–IL‐6 signaling crosstalk driving pain and identify EGF signaling as a key regulator of
Zhenzhen Yin, Limeng Wu, Yanling Zhang, Yao Sun, Grace Y. Lee, Simeng Lu, Xing Gao, John W. Chen, Sonu Subudhi, William Ho, Chao Zhu, Jun Ren, Gino B. Ferraro, Alona Muzikansky, Anat Stemmer‐Rachamimov, Jianren Mao, Scott R. Plotkin, Lei Xu   +17 more
wiley   +1 more source

Assessing nursing students' clinical competence in caring for LGBT+ clients: a cross-sectional study in Hong Kong. [PDF]

J Res Nurs
Ma H, Cham CYC, Zhang W, Tang SK, Ng AYM, Ho S, Wong JY.   +6 more
europepmc   +1 more source

Assessing clinical competence. [PDF]

BMJ, 1989
openaire   +2 more sources

An Artificial Antibody‐Based Toolbox Accelerates Validation of Hidden Microproteins Encoded by the Dark Genome

Advanced Science, EarlyView.
Microproteins are hidden treasures encoded by the “dark proteome” but remain largely underexplored due to the lack of highly efficient tools. We developed a molecularly imprinted polymers (MIPs)‐based toolbox (CLAIMID) to achieve accelerated and ultrasensitive microproteins validation at multiple biological scales (single living cells, cell populations,
Hui He, Anqi Zhang, Zhanchen Guo, Qi Li, Song Gao, Wenyan Guan, Ying Li, Jingran Chen, Sijia Sun, Jian He, Zhen Liu   +10 more
wiley   +1 more source

A Comparative Analysis of Objective Structured Clinical Examinations (OSCEs) and Traditional Written Exams in Medical Education for Assessing Clinical Competence. [PDF]

Cureus
G P, Hareesh GSR, Jasti LM, Chandrika H.
europepmc   +1 more source